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• W1482743441 abstract "Synaptic retraction occurs when the presynaptic nerve terminal withdraws from the postsynaptic structure. This process occurs both during development where it is especially prevalent during the process of synapse elimination, and throughout life as synapses change shape and size during synaptic remodeling. While much is known about the cellular mechanisms that control the formation of the synapse, relatively little is known about the cellular mechanisms that function during the retraction of a synapse. The smallest unit of the synapse must be the molecules that together form that cellular structure. Thus, to understand the formation of the synapse one must understand how those molecules come to be located at the synapse, while to understand synaptic retraction one must know how or if those molecules are removed from the synapse. In this article I will consider changes in the distribution of acetylcholinesterase, acetylcholine receptors, agrin, presynaptic molecules, synapse specific carbohydrates and other synapse specific molecules during synaptic retraction. By determining how these molecules are controlled during synapse formation and retraction, the basic mechanisms that control synapse formation and elimination may be determined." @default.
• W1482743441 created "2016-06-24" @default.
• W1482743441 creator A5023973125 @default.
• W1482743441 date "1997-01-01" @default.
• W1482743441 modified "2023-09-23" @default.
• W1482743441 title "Changes in the Distribution of Synapse Specific Molecules at the Neuromuscular Junction upon Synaptic Retraction" @default.
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• W1482743441 doi "https://doi.org/10.1016/s1569-2590(08)60180-9" @default.
• W1482743441 hasPublicationYear "1997" @default.
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