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- W1482808338 endingPage "91" @default.
- W1482808338 startingPage "61" @default.
- W1482808338 abstract "The intestinal microflora of mammals includes organisms with many unique molecules that enable them to modulate their immediate environment and thus to survive and reside successfully in the gut. Little is known about how individual molecules from these microbes affect the host's health and development, but the microbiome is considered a crucial factor in intestinal homeostasis. The literature highlights numerous ways in which the microflora stimulates the mammalian host's immune system, starting with its development and continuing to the initiation and resolution of inflammation. The influence of the microflora on the host's immune system is mediated principally by interactions with various antigen-presenting cells of the gut; these interactions result in substantial modulation of both the innate and the adaptive arms of the immune system. Certain polysaccharide antigens from the capsules of some commensal bacteria represent a functional class of molecules that exert profound immunomodulatory effects. Because of their unique structural features, including a zwitterionic charge motif, these polysaccharides can participate to a significant extent in the orchestration of host immune homeostasis. These molecules can be used to elucidate the basic biology of the mammalian intestine and have the potential for use in novel therapeutic regimens for various systemic or intestinal pathological conditions." @default.
- W1482808338 created "2016-06-24" @default.
- W1482808338 creator A5074817052 @default.
- W1482808338 creator A5077100355 @default.
- W1482808338 date "2010-01-01" @default.
- W1482808338 modified "2023-10-17" @default.
- W1482808338 title "Novel Tools for Modulating Immune Responses in the Host—Polysaccharides from the Capsule of Commensal Bacteria" @default.
- W1482808338 cites W1503222294 @default.
- W1482808338 cites W1505037806 @default.
- W1482808338 cites W1512595753 @default.
- W1482808338 cites W1566203300 @default.
- W1482808338 cites W1581904411 @default.
- W1482808338 cites W1601070312 @default.
- W1482808338 cites W1845975704 @default.
- W1482808338 cites W1901931884 @default.
- W1482808338 cites W1950704496 @default.
- W1482808338 cites W1964182398 @default.
- W1482808338 cites W1964286278 @default.
- W1482808338 cites W1967217097 @default.
- W1482808338 cites W1970620760 @default.
- W1482808338 cites W1971119469 @default.
- W1482808338 cites W1972473113 @default.
- W1482808338 cites W1973834362 @default.
- W1482808338 cites W1975164490 @default.
- W1482808338 cites W1975929837 @default.
- W1482808338 cites W1977831876 @default.
- W1482808338 cites W1980914602 @default.
- W1482808338 cites W1983972858 @default.
- W1482808338 cites W1988183869 @default.
- W1482808338 cites W1988318286 @default.
- W1482808338 cites W1991804457 @default.
- W1482808338 cites W1993187510 @default.
- W1482808338 cites W1995359262 @default.
- W1482808338 cites W1996454579 @default.
- W1482808338 cites W1998995307 @default.
- W1482808338 cites W2002625811 @default.
- W1482808338 cites W2004186675 @default.
- W1482808338 cites W2004751481 @default.
- W1482808338 cites W2005507128 @default.
- W1482808338 cites W2007220082 @default.
- W1482808338 cites W2007490062 @default.
- W1482808338 cites W2009938323 @default.
- W1482808338 cites W2010011171 @default.
- W1482808338 cites W2011778539 @default.
- W1482808338 cites W2012923521 @default.
- W1482808338 cites W2015812428 @default.
- W1482808338 cites W2016537283 @default.
- W1482808338 cites W2018505426 @default.
- W1482808338 cites W2022338512 @default.
- W1482808338 cites W2024263435 @default.
- W1482808338 cites W2035376710 @default.
- W1482808338 cites W2035506432 @default.
- W1482808338 cites W2036500213 @default.
- W1482808338 cites W2038131331 @default.
- W1482808338 cites W2039347592 @default.
- W1482808338 cites W2039605189 @default.
- W1482808338 cites W2042045767 @default.
- W1482808338 cites W2043620021 @default.
- W1482808338 cites W2047595952 @default.
- W1482808338 cites W2050417626 @default.
- W1482808338 cites W2050918847 @default.
- W1482808338 cites W2051529467 @default.
- W1482808338 cites W2053551865 @default.
- W1482808338 cites W2053891457 @default.
- W1482808338 cites W2054570291 @default.
- W1482808338 cites W2055959752 @default.
- W1482808338 cites W2056013354 @default.
- W1482808338 cites W2059839808 @default.
- W1482808338 cites W2062363040 @default.
- W1482808338 cites W2062800186 @default.
- W1482808338 cites W2064355487 @default.
- W1482808338 cites W2066203385 @default.
- W1482808338 cites W2069388628 @default.
- W1482808338 cites W2069571875 @default.
- W1482808338 cites W2070413937 @default.
- W1482808338 cites W2072417345 @default.
- W1482808338 cites W2075078512 @default.
- W1482808338 cites W2082904820 @default.
- W1482808338 cites W2083089709 @default.
- W1482808338 cites W2084150021 @default.
- W1482808338 cites W2085022819 @default.
- W1482808338 cites W2086947528 @default.
- W1482808338 cites W2088553840 @default.
- W1482808338 cites W2089646349 @default.
- W1482808338 cites W2090640877 @default.
- W1482808338 cites W2090925778 @default.
- W1482808338 cites W2092653359 @default.
- W1482808338 cites W2093531092 @default.
- W1482808338 cites W2097697877 @default.
- W1482808338 cites W2099376515 @default.
- W1482808338 cites W2101203073 @default.
- W1482808338 cites W2101363646 @default.
- W1482808338 cites W2105221079 @default.
- W1482808338 cites W2106132036 @default.
- W1482808338 cites W2106829739 @default.
- W1482808338 cites W2107066107 @default.
- W1482808338 cites W2108064918 @default.
- W1482808338 cites W2110957620 @default.