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- W1482839084 abstract "This review briefly describes the cellular distribution and documented roles of the transforming growth factor (TGF)-beta isoforms TGF-beta2 and -beta3 in the central and peripheral nervous system. TGF-beta2 and -beta3 are coexpressed in developing radial glial and mature astroglial and Schwann cells, as well as in subpopulations of differentiated neurons, most prominently in cortical, hippocampal, and brainstem/spinal cord motor neurons. In vitro studies have suggested a number of potential, physiologically relevant functions for TGF-betas including regulation of astroglial cell proliferation, expression of adhesion molecules, survival promoting roles for neurons in combination with established neurotrophic factors, and differentiative actions on neurons." @default.
- W1482839084 created "2016-06-24" @default.
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- W1482839084 date "2000-12-01" @default.
- W1482839084 modified "2023-10-17" @default.
- W1482839084 title "Functions of transforming growth factor-β isoforms in the nervous system" @default.
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- W1482839084 doi "https://doi.org/10.1046/j.1432-1327.2000.01824.x" @default.
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