FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1483332234> ?p ?o ?g. }

• W1483332234 endingPage "73" @default.
• W1483332234 startingPage "63" @default.
• W1483332234 abstract "This study is the first to report that Spirulina complex polysaccharides (CPS) suppress glioma growth by down-regulating angiogenesis via a Toll-like receptor 4 signal. Murine RSV-M glioma cells were implanted s.c. into C3H/HeN mice and TLR4 mutant C3H/HeJ mice. Treatment with either Spirulina CPS or Escherichia coli (E. coli) lipopolysaccharides (LPS) strongly suppressed RSV-M glioma cell growth in C3H/HeN, but not C3H/HeJ, mice. Glioma cells stimulated production of interleukin (IL)-17 in both C3H/HeN and C3H/HeJ tumor-bearing mice. Treatment with E. coli LPS induced much greater IL-17 production in tumor-bearing C3H/HeN mice than in tumor-bearing C3H/HeJ mice. In C3H/HeN mice, treatment with Spirulina CPS suppressed growth of re-transplanted glioma; however, treatment with E. coli LPS did not, suggesting that Spirulina CPS enhance the immune response. Administration of anti-cluster of differentiation (CD)8, anti-CD4, anti-CD8 antibodies, and anti-asialo GM1 antibodies enhanced tumor growth, suggesting that T cells and natural killer cells or macrophages are involved in suppression of tumor growth by Spirulina CPS. Although anti-interferon-γ antibodies had no effect on glioma cell growth, anti-IL-17 antibodies administered four days after tumor transplantation suppressed growth similarly to treatment with Spirulina CPS. Less angiogenesis was observed in gliomas from Spirulina CPS-treated mice than in those from saline- or E. coli LPS-treated mice. These findings suggest that, in C3H/HeN mice, Spirulina CPS antagonize glioma cell growth by down-regulating angiogenesis, and that this down-regulation is mediated in part by regulating IL-17 production." @default.
• W1483332234 created "2016-06-24" @default.
• W1483332234 creator A5020517072 @default.
• W1483332234 creator A5029475928 @default.
• W1483332234 creator A5030242147 @default.
• W1483332234 creator A5052701519 @default.
• W1483332234 creator A5062293147 @default.
• W1483332234 creator A5079444709 @default.
• W1483332234 creator A5079622194 @default.
• W1483332234 creator A5082060300 @default.
• W1483332234 creator A5087021732 @default.
• W1483332234 creator A5090513725 @default.
• W1483332234 date "2013-01-01" @default.
• W1483332234 modified "2023-10-16" @default.
• W1483332234 title "Regulatory effects of<i>Spirulina</i>complex polysaccharides on growth of murine RSV-M glioma cells through Toll-like receptor 4" @default.
• W1483332234 cites W1642873092 @default.
• W1483332234 cites W1655860314 @default.
• W1483332234 cites W1928584722 @default.
• W1483332234 cites W1968134126 @default.
• W1483332234 cites W1983946589 @default.
• W1483332234 cites W1984467626 @default.
• W1483332234 cites W1987722093 @default.
• W1483332234 cites W1987915516 @default.
• W1483332234 cites W1991432849 @default.
• W1483332234 cites W2000102677 @default.
• W1483332234 cites W2024490058 @default.
• W1483332234 cites W2049094526 @default.
• W1483332234 cites W2050557162 @default.
• W1483332234 cites W2068119757 @default.
• W1483332234 cites W2074067501 @default.
• W1483332234 cites W2089262366 @default.
• W1483332234 cites W2090171472 @default.
• W1483332234 cites W2107715779 @default.
• W1483332234 cites W2115909201 @default.
• W1483332234 cites W2120227455 @default.
• W1483332234 cites W2128728003 @default.
• W1483332234 cites W2129319296 @default.
• W1483332234 cites W2131419135 @default.
• W1483332234 cites W2131943372 @default.
• W1483332234 cites W2156451877 @default.
• W1483332234 cites W2172466148 @default.
• W1483332234 cites W2271816523 @default.
• W1483332234 doi "https://doi.org/10.1111/1348-0421.12001" @default.
• W1483332234 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23134155" @default.
• W1483332234 hasPublicationYear "2013" @default.
• W1483332234 type Work @default.
• W1483332234 sameAs 1483332234 @default.
• W1483332234 citedByCount "29" @default.
• W1483332234 countsByYear W14833322342013 @default.
• W1483332234 countsByYear W14833322342014 @default.
• W1483332234 countsByYear W14833322342015 @default.
• W1483332234 countsByYear W14833322342016 @default.
• W1483332234 countsByYear W14833322342017 @default.
• W1483332234 countsByYear W14833322342019 @default.
• W1483332234 countsByYear W14833322342020 @default.
• W1483332234 countsByYear W14833322342021 @default.
• W1483332234 countsByYear W14833322342022 @default.
• W1483332234 countsByYear W14833322342023 @default.
• W1483332234 crossrefType "journal-article" @default.
• W1483332234 hasAuthorship W1483332234A5020517072 @default.
• W1483332234 hasAuthorship W1483332234A5029475928 @default.
• W1483332234 hasAuthorship W1483332234A5030242147 @default.
• W1483332234 hasAuthorship W1483332234A5052701519 @default.
• W1483332234 hasAuthorship W1483332234A5062293147 @default.
• W1483332234 hasAuthorship W1483332234A5079444709 @default.
• W1483332234 hasAuthorship W1483332234A5079622194 @default.
• W1483332234 hasAuthorship W1483332234A5082060300 @default.
• W1483332234 hasAuthorship W1483332234A5087021732 @default.
• W1483332234 hasAuthorship W1483332234A5090513725 @default.
• W1483332234 hasBestOaLocation W14833322341 @default.
• W1483332234 hasConcept C153911025 @default.
• W1483332234 hasConcept C159654299 @default.
• W1483332234 hasConcept C167672396 @default.
• W1483332234 hasConcept C18903297 @default.
• W1483332234 hasConcept C203014093 @default.
• W1483332234 hasConcept C206139338 @default.
• W1483332234 hasConcept C2778227246 @default.
• W1483332234 hasConcept C2779784034 @default.
• W1483332234 hasConcept C2780394083 @default.
• W1483332234 hasConcept C502942594 @default.
• W1483332234 hasConcept C55493867 @default.
• W1483332234 hasConcept C62112901 @default.
• W1483332234 hasConcept C86803240 @default.
• W1483332234 hasConcept C8891405 @default.
• W1483332234 hasConcept C89423630 @default.
• W1483332234 hasConceptScore W1483332234C153911025 @default.
• W1483332234 hasConceptScore W1483332234C159654299 @default.
• W1483332234 hasConceptScore W1483332234C167672396 @default.
• W1483332234 hasConceptScore W1483332234C18903297 @default.
• W1483332234 hasConceptScore W1483332234C203014093 @default.
• W1483332234 hasConceptScore W1483332234C206139338 @default.
• W1483332234 hasConceptScore W1483332234C2778227246 @default.
• W1483332234 hasConceptScore W1483332234C2779784034 @default.
• W1483332234 hasConceptScore W1483332234C2780394083 @default.
• W1483332234 hasConceptScore W1483332234C502942594 @default.
• W1483332234 hasConceptScore W1483332234C55493867 @default.
• W1483332234 hasConceptScore W1483332234C62112901 @default.
• W1483332234 hasConceptScore W1483332234C86803240 @default.

• next