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- W1483524720 abstract "The Influence of Various Clinical Parameters on the Pregnancy Rates after Cryopreservation of Human Prenuclear Oocytes It has been the aim of this work to examine the ability of human fertilized eggs in the pronucleus state to develop and implant under different clinical and methodical conditions.(patients age, cause of sterility, primary or secondary sterility, stimulation regimes, method of fertilization, duration of cryopreservation, number and developmental stage of embryos transferred). Patients with primary sterility conceived significantly less (7,5%) than those with secondary sterility (15,2%). Patients, who had already been pregnant once by artificial reproduction techniques (ART as IVF or ICSI) had also a higher chance to conceive once more by another ART (15,4%). The age of the women up to 40 years was of no significance concerning the fertilizationand pregnancy-rate. Looking on the reasons for sterility, the “idiopathic” was the most promising (pregnancy rate 14,9%) but there were only minor differences between male, female, organic and functional causes. When both genders exhibited reasons for infertility, the pregnancy rate decreased to 6,7%. The different agents used for stimulation in the eggsampling cycle showed differences to some extend, namely 55,6% after HMGstimulation in contrast to 63,1% after FSH stimulation. The survival rate after thawing the PN-cells was lower after HMG stimulation (60,2%) than after FSH stimulation (67,7%). Otherwise the pregnancy rate did not show remarkable differences (9,6% bzw. 10,8%). The pre-treatment of the cryotransfer cycle was very decisive, as the cryotransfer in the unmedicated spontaneous cycle was the most successful with a pregnancy-rate of 15,7%. The stimulation with Clomipene-Citrate as well as low-dose Gonadotrophin application was also rather successful (14,3%)" @default.
- W1483524720 created "2016-06-24" @default.
- W1483524720 creator A5068461476 @default.
- W1483524720 date "2008-01-01" @default.
- W1483524720 modified "2023-09-26" @default.
- W1483524720 title "Einfluss verschiedener klinischer Parameter auf die Erfolgsrate nachKryokonservierung imprägnierter menschlicher Eizellen" @default.
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