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• W1484290743 abstract "Abstract Group B Streptococcus (GBS) is a major cause of invasive disease in neonates in the United States. Surveillance of invasive GBS disease in Minnesota, USA, during 2000–2010 yielded 449 isolates from 449 infants; 257 had early-onset (EO) disease (by age 6 days) and 192 late-onset (LO) disease (180 at age 7–89 days, 12 at age 90–180 days). Isolates were characterized by capsular polysaccharide serotype and surface-protein profile; types III and Ia predominated. However, because previously uncommon serotype IV constitutes 5/31 EO isolates in 2010, twelve type IV isolates collected during 2000–2010 were studied further. By pulsed-field gel electrophoresis, they were classified into 3 profiles; by multilocus sequence typing, representative isolates included new sequence type 468. Resistance to clindamycin or erythromycin was detected in 4/5 serotype IV isolates. Emergence of serotype IV GBS in Minnesota highlights the need for serotype prevalence monitoring to detect trends that could affect prevention strategies." @default.
• W1484290743 created "2016-06-24" @default.
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• W1484290743 date "2013-04-01" @default.
• W1484290743 modified "2023-10-16" @default.
• W1484290743 title "Serotype IV and Invasive Group B<i>Streptococcus</i>Disease in Neonates, Minnesota, USA, 2000–20101" @default.
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• W1484290743 doi "https://doi.org/10.3201/eid1904.121572" @default.
• W1484290743 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3647718" @default.
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