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• W1484359922 abstract "Neuroendocrine tumours (NETs) are rare and heterogeneous neoplasms with variable bio‐ logical behaviour. The estimated incidence of NETs is about 1-5 cases/100,000/year. The most recent data show a progressive increase of the incidence in the last years and a high increase of their prevalence and survival [1]. NETs can be sporadic or can arise in complex hereditary endocrine disorders such as Multiple Endocrine Neoplasias (MENs), Familial Paragangliomatosis (FPGLs), Neurofibromatosis type 1 (NF1), von Hippel-Lindau Disease (VHL), Tuberous Sclerosis (TSC) [1]. It has been estimated that hereditary NETs occurrence varies with site of origin of the tumour, ranging 5 to 30% of cases [1]. Due to the recent ad‐ vances in the knowledge of biology and genetics of NETs, these rates seems to be an under‐ estimation and novel mutations of well known oncogenes or tumour suppressor genes as well as new genes and molecular pathways responsible for unknown syndromes are expect‐ ed to be characterized." @default.
• W1484359922 created "2016-06-24" @default.
• W1484359922 creator A5012196997 @default.
• W1484359922 creator A5018880335 @default.
• W1484359922 creator A5025013672 @default.
• W1484359922 creator A5070034601 @default.
• W1484359922 date "2013-05-08" @default.
• W1484359922 modified "2023-10-03" @default.
• W1484359922 title "Hereditary Neuroendocrine Tumor Syndromes" @default.
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