FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1484394993> ?p ?o ?g. }

• W1484394993 endingPage "754" @default.
• W1484394993 startingPage "748" @default.
• W1484394993 abstract "There is emerging evidence of the role of diabetes as a risk factor for frailty. However, the mechanisms of this association are uncertain.Prospective cohort study of 1750 noninstitutionalized individuals aged 60 years or older recruited in 2008-2010. At baseline, information was obtained on health behaviors, morbidity, cardiometabolic biomarkers, and antidiabetic treatments. Individuals were considered diabetic if they reported a physician diagnosis or had fasting serum glucose of 126 mg/dL or higher. Study participants were followed through 2012 to assess incident frailty, defined as at least 3 of the 5 Fried criteria.At baseline, the cohort included 346 individuals with diabetes and 1404 without diabetes. Over a mean 3.5-year follow-up, 115 cases of incident frailty were ascertained. After adjustment for age, sex, and education, participants with diabetes showed an increased risk of frailty (odds ratio [OR] 2.18, 95% confidence interval [CI] 1.42-3.37). Additional adjustment for health behaviors and abdominal obesity yielded a 29.7% reduction in the OR (OR 1.83, 95% CI 1.16-2.90). Subsequent adjustment for morbidity produced an additional 8.4% reduction (OR 1.76, 95% CI 1.10-2.82), and for cardiometabolic biomarkers, a further 44% reduction (OR 1.32, 95% CI 0.70-2.49). In particular, adjustment for HbA1c, lipoproteins, and triglycerides accounted for the greatest reductions. Finally, additional adjustment for oral antidiabetic medication reduced the OR to 1.01 (95% CI 0.46-2.20), whereas adjustment for nutritional therapy increased the OR to 1.64 (95% CI 0.77-3.49).Diabetes mellitus is associated with higher risk of frailty; this association is partly explained by unhealthy behaviors and obesity and, to a greater extent, by poor glucose control and altered serum lipid profile among diabetic individuals. Conversely, diabetes nutritional therapy reduces the risk of frailty." @default.
• W1484394993 created "2016-06-24" @default.
• W1484394993 creator A5004792362 @default.
• W1484394993 creator A5010973224 @default.
• W1484394993 creator A5017208361 @default.
• W1484394993 creator A5025295025 @default.
• W1484394993 creator A5053996122 @default.
• W1484394993 creator A5088005811 @default.
• W1484394993 date "2015-09-01" @default.
• W1484394993 modified "2023-10-17" @default.
• W1484394993 title "Diabetes and Risk of Frailty and Its Potential Mechanisms: A Prospective Cohort Study of Older Adults" @default.
• W1484394993 cites W1485299415 @default.
• W1484394993 cites W1576645826 @default.
• W1484394993 cites W1634000265 @default.
• W1484394993 cites W1976892379 @default.
• W1484394993 cites W1983722103 @default.
• W1484394993 cites W1985992465 @default.
• W1484394993 cites W2005848242 @default.
• W1484394993 cites W2007581359 @default.
• W1484394993 cites W2011907634 @default.
• W1484394993 cites W2012553671 @default.
• W1484394993 cites W2014759828 @default.
• W1484394993 cites W2019200806 @default.
• W1484394993 cites W2019724009 @default.
• W1484394993 cites W2039221207 @default.
• W1484394993 cites W2057672757 @default.
• W1484394993 cites W2061049831 @default.
• W1484394993 cites W2078965485 @default.
• W1484394993 cites W2088746564 @default.
• W1484394993 cites W2096697496 @default.
• W1484394993 cites W2098911616 @default.
• W1484394993 cites W2099281324 @default.
• W1484394993 cites W2101489273 @default.
• W1484394993 cites W2103784531 @default.
• W1484394993 cites W2108944512 @default.
• W1484394993 cites W2110664743 @default.
• W1484394993 cites W2121346841 @default.
• W1484394993 cites W2126975151 @default.
• W1484394993 cites W2129871296 @default.
• W1484394993 cites W2132748892 @default.
• W1484394993 cites W2134822179 @default.
• W1484394993 cites W2137289133 @default.
• W1484394993 cites W2139199691 @default.
• W1484394993 cites W2142514031 @default.
• W1484394993 cites W2145863072 @default.
• W1484394993 cites W2147019179 @default.
• W1484394993 cites W2147944762 @default.
• W1484394993 cites W2153993473 @default.
• W1484394993 cites W2161662405 @default.
• W1484394993 cites W2162983983 @default.
• W1484394993 cites W2164059021 @default.
• W1484394993 cites W2164208500 @default.
• W1484394993 cites W2166733955 @default.
• W1484394993 cites W2166895293 @default.
• W1484394993 cites W2168619351 @default.
• W1484394993 cites W4212814507 @default.
• W1484394993 doi "https://doi.org/10.1016/j.jamda.2015.04.008" @default.
• W1484394993 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25986874" @default.
• W1484394993 hasPublicationYear "2015" @default.
• W1484394993 type Work @default.
• W1484394993 sameAs 1484394993 @default.
• W1484394993 citedByCount "118" @default.
• W1484394993 countsByYear W14843949932015 @default.
• W1484394993 countsByYear W14843949932016 @default.
• W1484394993 countsByYear W14843949932017 @default.
• W1484394993 countsByYear W14843949932018 @default.
• W1484394993 countsByYear W14843949932019 @default.
• W1484394993 countsByYear W14843949932020 @default.
• W1484394993 countsByYear W14843949932021 @default.
• W1484394993 countsByYear W14843949932022 @default.
• W1484394993 countsByYear W14843949932023 @default.
• W1484394993 crossrefType "journal-article" @default.
• W1484394993 hasAuthorship W1484394993A5004792362 @default.
• W1484394993 hasAuthorship W1484394993A5010973224 @default.
• W1484394993 hasAuthorship W1484394993A5017208361 @default.
• W1484394993 hasAuthorship W1484394993A5025295025 @default.
• W1484394993 hasAuthorship W1484394993A5053996122 @default.
• W1484394993 hasAuthorship W1484394993A5088005811 @default.
• W1484394993 hasBestOaLocation W14843949932 @default.
• W1484394993 hasConcept C126322002 @default.
• W1484394993 hasConcept C134018914 @default.
• W1484394993 hasConcept C156957248 @default.
• W1484394993 hasConcept C188816634 @default.
• W1484394993 hasConcept C201903717 @default.
• W1484394993 hasConcept C2777693730 @default.
• W1484394993 hasConcept C2780578515 @default.
• W1484394993 hasConcept C44249647 @default.
• W1484394993 hasConcept C511355011 @default.
• W1484394993 hasConcept C555293320 @default.
• W1484394993 hasConcept C71924100 @default.
• W1484394993 hasConcept C72563966 @default.
• W1484394993 hasConceptScore W1484394993C126322002 @default.
• W1484394993 hasConceptScore W1484394993C134018914 @default.
• W1484394993 hasConceptScore W1484394993C156957248 @default.
• W1484394993 hasConceptScore W1484394993C188816634 @default.
• W1484394993 hasConceptScore W1484394993C201903717 @default.
• W1484394993 hasConceptScore W1484394993C2777693730 @default.
• W1484394993 hasConceptScore W1484394993C2780578515 @default.

• next