Matches in SemOpenAlex for { <https://semopenalex.org/work/W1484665310> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W1484665310 endingPage "244" @default.
- W1484665310 startingPage "226" @default.
- W1484665310 abstract "As an alternative strategy to the use of proteolytic and chemical cleavage in the production of fragments of immunoglobulins retaining Fc effector functions. peptides representative of amino acid sequences constituting the putative active sites have been synthesized and assessed for biological activity in various in vitro systems. This approach has been adopted in attempts to define more precisely the autoantigenic epitope on human IgG against which anti-γ-globulin antibodies (the so-called general ‘rheumatoid factors’). found in the sera and joint fluids of patients with rheumatoid arthritis. are directed. Synthetic peptides representative of ϵ-chain sequences are being used in the production of antibodies (polyclonal and monoclonal) directed against specific epitopes within the Fc regions of human and rat IgE. The ability of these antisera to influence the in vitro functional properties of IgE anaphylactic antibodies is now under investigation, with particular attention being focused on cytophilicity and mast cell triggering. Preliminary findings suggest that certain of the antisera might be capable of inhibiting mast cell sensitization by IgE antibodies. and therefore might form the basis of a new type of anti-allergy compound." @default.
- W1484665310 created "2016-06-24" @default.
- W1484665310 creator A5036391481 @default.
- W1484665310 creator A5059245231 @default.
- W1484665310 creator A5081779167 @default.
- W1484665310 date "2007-09-28" @default.
- W1484665310 modified "2023-09-23" @default.
- W1484665310 title "The use of Synthetic Peptides in the Delineation of Immunoglobulin Antigenic Epitopes and Fc Effector Functions" @default.
- W1484665310 cites W1551634200 @default.
- W1484665310 cites W1557858929 @default.
- W1484665310 cites W1892656282 @default.
- W1484665310 cites W1965399166 @default.
- W1484665310 cites W1965448491 @default.
- W1484665310 cites W1968353217 @default.
- W1484665310 cites W1970968408 @default.
- W1484665310 cites W1997601409 @default.
- W1484665310 cites W2000728769 @default.
- W1484665310 cites W2005010882 @default.
- W1484665310 cites W2015125932 @default.
- W1484665310 cites W2022579820 @default.
- W1484665310 cites W2030587815 @default.
- W1484665310 cites W2036467348 @default.
- W1484665310 cites W2057878630 @default.
- W1484665310 cites W2090944191 @default.
- W1484665310 cites W2093944259 @default.
- W1484665310 cites W2113711531 @default.
- W1484665310 cites W2272339894 @default.
- W1484665310 cites W2320556745 @default.
- W1484665310 cites W2332185610 @default.
- W1484665310 cites W2344044959 @default.
- W1484665310 cites W2410717008 @default.
- W1484665310 cites W4293253343 @default.
- W1484665310 doi "https://doi.org/10.1002/9780470513286.ch13" @default.
- W1484665310 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2426054" @default.
- W1484665310 hasPublicationYear "2007" @default.
- W1484665310 type Work @default.
- W1484665310 sameAs 1484665310 @default.
- W1484665310 citedByCount "2" @default.
- W1484665310 crossrefType "other" @default.
- W1484665310 hasAuthorship W1484665310A5036391481 @default.
- W1484665310 hasAuthorship W1484665310A5059245231 @default.
- W1484665310 hasAuthorship W1484665310A5081779167 @default.
- W1484665310 hasConcept C141105273 @default.
- W1484665310 hasConcept C147483822 @default.
- W1484665310 hasConcept C159654299 @default.
- W1484665310 hasConcept C185592680 @default.
- W1484665310 hasConcept C195616568 @default.
- W1484665310 hasConcept C202751555 @default.
- W1484665310 hasConcept C203014093 @default.
- W1484665310 hasConcept C51785407 @default.
- W1484665310 hasConcept C542903549 @default.
- W1484665310 hasConcept C55493867 @default.
- W1484665310 hasConcept C86803240 @default.
- W1484665310 hasConcept C91523082 @default.
- W1484665310 hasConcept C956191 @default.
- W1484665310 hasConceptScore W1484665310C141105273 @default.
- W1484665310 hasConceptScore W1484665310C147483822 @default.
- W1484665310 hasConceptScore W1484665310C159654299 @default.
- W1484665310 hasConceptScore W1484665310C185592680 @default.
- W1484665310 hasConceptScore W1484665310C195616568 @default.
- W1484665310 hasConceptScore W1484665310C202751555 @default.
- W1484665310 hasConceptScore W1484665310C203014093 @default.
- W1484665310 hasConceptScore W1484665310C51785407 @default.
- W1484665310 hasConceptScore W1484665310C542903549 @default.
- W1484665310 hasConceptScore W1484665310C55493867 @default.
- W1484665310 hasConceptScore W1484665310C86803240 @default.
- W1484665310 hasConceptScore W1484665310C91523082 @default.
- W1484665310 hasConceptScore W1484665310C956191 @default.
- W1484665310 hasLocation W14846653101 @default.
- W1484665310 hasLocation W14846653102 @default.
- W1484665310 hasOpenAccess W1484665310 @default.
- W1484665310 hasPrimaryLocation W14846653101 @default.
- W1484665310 hasRelatedWork W1604248381 @default.
- W1484665310 hasRelatedWork W1710368821 @default.
- W1484665310 hasRelatedWork W1856187979 @default.
- W1484665310 hasRelatedWork W2025678534 @default.
- W1484665310 hasRelatedWork W2057918160 @default.
- W1484665310 hasRelatedWork W2095527878 @default.
- W1484665310 hasRelatedWork W2146940419 @default.
- W1484665310 hasRelatedWork W2386118910 @default.
- W1484665310 hasRelatedWork W4206011279 @default.
- W1484665310 hasRelatedWork W4239344034 @default.
- W1484665310 isParatext "false" @default.
- W1484665310 isRetracted "false" @default.
- W1484665310 magId "1484665310" @default.
- W1484665310 workType "other" @default.