Matches in SemOpenAlex for { <https://semopenalex.org/work/W1484865800> ?p ?o ?g. }
- W1484865800 endingPage "537" @default.
- W1484865800 startingPage "529" @default.
- W1484865800 abstract "Studies involving the direct measurement of clinical response to inhaled asthma drugs, especially inhaled corticosteroids, may be very difficult to conduct. However, the deposition of drug in the lungs may be considered as a measure of local bioavailability, and may be quantified by radionuclide imaging techniques, or for some drugs by pharmacokinetic methods. This paper reviews evidence for considering lung deposition data as a surrogate for the clinical response to inhaled asthma drugs, based mainly upon a series of case histories. The appropriate use of lung deposition data in regulatory packages, especially to document the equivalence or comparability of two products, offers the possibility of significant time saving in the drug development process, and hence a faster drug development programme for inhaled asthma products." @default.
- W1484865800 created "2016-06-24" @default.
- W1484865800 creator A5041918036 @default.
- W1484865800 date "2000-06-01" @default.
- W1484865800 modified "2023-09-25" @default.
- W1484865800 title "Can lung deposition data act as a surrogate for the clinical response to inhaled asthma drugs?" @default.
- W1484865800 cites W1529317955 @default.
- W1484865800 cites W1963707897 @default.
- W1484865800 cites W1983173561 @default.
- W1484865800 cites W1983366056 @default.
- W1484865800 cites W1986186916 @default.
- W1484865800 cites W1998433520 @default.
- W1484865800 cites W2006545949 @default.
- W1484865800 cites W2008742573 @default.
- W1484865800 cites W2010566912 @default.
- W1484865800 cites W2024632863 @default.
- W1484865800 cites W2035904992 @default.
- W1484865800 cites W2037364728 @default.
- W1484865800 cites W2054806186 @default.
- W1484865800 cites W2069442723 @default.
- W1484865800 cites W2074557134 @default.
- W1484865800 cites W2077793557 @default.
- W1484865800 cites W2079718411 @default.
- W1484865800 cites W2082530871 @default.
- W1484865800 cites W2089500181 @default.
- W1484865800 cites W2092724975 @default.
- W1484865800 cites W2093081174 @default.
- W1484865800 cites W2094777837 @default.
- W1484865800 cites W2096443693 @default.
- W1484865800 cites W2101975583 @default.
- W1484865800 cites W2107462455 @default.
- W1484865800 cites W2134494103 @default.
- W1484865800 cites W2140730458 @default.
- W1484865800 cites W2142564724 @default.
- W1484865800 cites W2156212492 @default.
- W1484865800 cites W2163347392 @default.
- W1484865800 cites W2184035260 @default.
- W1484865800 cites W2326289599 @default.
- W1484865800 cites W2405499044 @default.
- W1484865800 cites W2415229841 @default.
- W1484865800 cites W2590124738 @default.
- W1484865800 doi "https://doi.org/10.1046/j.1365-2125.2000.00106.x" @default.
- W1484865800 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2015044" @default.
- W1484865800 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10848716" @default.
- W1484865800 hasPublicationYear "2000" @default.
- W1484865800 type Work @default.
- W1484865800 sameAs 1484865800 @default.
- W1484865800 citedByCount "32" @default.
- W1484865800 countsByYear W14848658002012 @default.
- W1484865800 countsByYear W14848658002013 @default.
- W1484865800 countsByYear W14848658002014 @default.
- W1484865800 countsByYear W14848658002015 @default.
- W1484865800 countsByYear W14848658002016 @default.
- W1484865800 countsByYear W14848658002018 @default.
- W1484865800 countsByYear W14848658002019 @default.
- W1484865800 countsByYear W14848658002020 @default.
- W1484865800 countsByYear W14848658002022 @default.
- W1484865800 crossrefType "journal-article" @default.
- W1484865800 hasAuthorship W1484865800A5041918036 @default.
- W1484865800 hasBestOaLocation W14848658002 @default.
- W1484865800 hasConcept C112705442 @default.
- W1484865800 hasConcept C126322002 @default.
- W1484865800 hasConcept C177713679 @default.
- W1484865800 hasConcept C181389837 @default.
- W1484865800 hasConcept C2776042228 @default.
- W1484865800 hasConcept C2776954882 @default.
- W1484865800 hasConcept C2780035454 @default.
- W1484865800 hasConcept C42219234 @default.
- W1484865800 hasConcept C64903051 @default.
- W1484865800 hasConcept C71924100 @default.
- W1484865800 hasConcept C98274493 @default.
- W1484865800 hasConceptScore W1484865800C112705442 @default.
- W1484865800 hasConceptScore W1484865800C126322002 @default.
- W1484865800 hasConceptScore W1484865800C177713679 @default.
- W1484865800 hasConceptScore W1484865800C181389837 @default.
- W1484865800 hasConceptScore W1484865800C2776042228 @default.
- W1484865800 hasConceptScore W1484865800C2776954882 @default.
- W1484865800 hasConceptScore W1484865800C2780035454 @default.
- W1484865800 hasConceptScore W1484865800C42219234 @default.
- W1484865800 hasConceptScore W1484865800C64903051 @default.
- W1484865800 hasConceptScore W1484865800C71924100 @default.
- W1484865800 hasConceptScore W1484865800C98274493 @default.
- W1484865800 hasIssue "6" @default.
- W1484865800 hasLocation W14848658001 @default.
- W1484865800 hasLocation W14848658002 @default.
- W1484865800 hasLocation W14848658003 @default.
- W1484865800 hasLocation W14848658004 @default.
- W1484865800 hasOpenAccess W1484865800 @default.
- W1484865800 hasPrimaryLocation W14848658001 @default.
- W1484865800 hasRelatedWork W1969876219 @default.
- W1484865800 hasRelatedWork W2047514526 @default.
- W1484865800 hasRelatedWork W2080955156 @default.
- W1484865800 hasRelatedWork W2350694022 @default.
- W1484865800 hasRelatedWork W2400119402 @default.
- W1484865800 hasRelatedWork W2990361423 @default.
- W1484865800 hasRelatedWork W2992077105 @default.
- W1484865800 hasRelatedWork W3024440267 @default.
- W1484865800 hasRelatedWork W3168471555 @default.