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- W1485087642 abstract "The ReProGlo assay uses murine embryonic stem cells stably transfected with a reporter vector for the Wnt/beta-catenin pathway. The impact of test chemicals on the activity of this pathway is used as an endpoint to predict the embryotoxicity of test chemicals. The assay is relatively fast (48 h) and cost-effective. Automation of the assay as well as integration of a metabolic activation system was shown to be feasible." @default.
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- W1485087642 date "2013-02-13" @default.
- W1485087642 modified "2023-10-16" @default.
- W1485087642 title "ReProGlo: A New Stem-Cell-Based High-Throughput Assay to Predict the Embryotoxic Potential of Chemicals" @default.
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- W1485087642 doi "https://doi.org/10.1002/9781118538203.ch18" @default.
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