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- W1485417013 abstract "Abstract : The goal of the research project, Time-Resolved and Spectroscopic Three-Dimensional Optical Breast Tomography, was to develop a safe and affordable breast cancer detection modality that uses noninvasive near-infrared (NIR) light for imaging and diagnosing tumors in human breast with high resolution and specificity. In order to realize that goal three different approaches were developed. These are Optical Tomography using Independent Component Analysis (OPTICA), Round Trip Matrix (RTM) approach, and Center of Intensity Time Gated Imaging (CITGI). OPTICA is the most developed of these approaches. It has been demonstrated that OPTICA can detect, obtain the threedimensional location information and cross-section images of small absorbing, scattering, and fluorescent targets in model media, and tumor(s) in realistic model breast with considerable accuracy. Further accomplishments include development of a forward model for determining the backscattered polarized light intensity distribution, and initial development of a technique to determine scattering coefficient, absorption coefficient, and anisotropy factor (g) of breast tissue specimens. Besides detection and localization of tumors in breast, these results may have potential applications in optical biopsy, and lumpectomy. The graduate student supported by the project received his Ph. D., adding another scientist to the ongoing fight against breast cancer." @default.
- W1485417013 created "2016-06-24" @default.
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- W1485417013 date "2006-04-01" @default.
- W1485417013 modified "2023-10-16" @default.
- W1485417013 title "Time-Resolved and Spectroscopic Three-Dimensional Optical Breast Tomography" @default.
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- W1485417013 doi "https://doi.org/10.21236/ada464218" @default.
- W1485417013 hasPublicationYear "2006" @default.
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