Matches in SemOpenAlex for { <https://semopenalex.org/work/W1485456429> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W1485456429 abstract "Lipoprotein changes often precede incident type 2 diabetes and may be diabetogenic, but effects of lipid-lowering medications, ethnicity and sex on these associations are unclear. In the Multi-Ethnic Study of Atherosclerosis, among 5636 men and women, ages 45-84, without baseline diabetes or CVD, 694 diabetes cases were identified during mean follow-up of 7.7 years. NMR spectroscopy was used to measure lipoprotein particle concentrations and size, including a calculated lipoprotein-related insulin resistance score (LP-IR), on baseline plasma. Analyses were stratified by baseline lipid-lowering medication (primarily statin) use, as “untreated” (n=4816) or “treated” (n=820), and by glucose <100 vs.100-125 mg/dl (impaired fasting glucose, IFG). Among treated and untreated participants, higher LP-IR, larger mean VLDL particle size, HOMA-IR and (log)insulin were associated with incident diabetes, adjusted for age, ethnicity and sex (HRs per SD >1.5, p<0.05). Associations of LP-IR and VLDL size with incident diabetes remained significant when additionally adjusted for HDL-C, (log) triglycerides, BMI, glucose, family history of diabetes, physical activity and alcohol use and among treated participants with IFG, and were similar by sex and race-ethnicity. In conclusion, lipoprotein particle measures, particularly LP-IR and VLDL size, were robustly associated with incident diabetes among both untreated and treated ethnically diverse adults." @default.
- W1485456429 created "2016-06-24" @default.
- W1485456429 creator A5005312014 @default.
- W1485456429 creator A5025347701 @default.
- W1485456429 creator A5031644011 @default.
- W1485456429 creator A5058511529 @default.
- W1485456429 creator A5061263756 @default.
- W1485456429 creator A5074749823 @default.
- W1485456429 creator A5090824996 @default.
- W1485456429 date "2014-03-25" @default.
- W1485456429 modified "2023-09-23" @default.
- W1485456429 title "Abstract 37: Lipoprotein Subclasses and Incident Type 2 Diabetes in the Multi-Ethnic Study of Atherosclerosis" @default.
- W1485456429 doi "https://doi.org/10.1161/circ.129.suppl_1.37" @default.
- W1485456429 hasPublicationYear "2014" @default.
- W1485456429 type Work @default.
- W1485456429 sameAs 1485456429 @default.
- W1485456429 citedByCount "0" @default.
- W1485456429 crossrefType "journal-article" @default.
- W1485456429 hasAuthorship W1485456429A5005312014 @default.
- W1485456429 hasAuthorship W1485456429A5025347701 @default.
- W1485456429 hasAuthorship W1485456429A5031644011 @default.
- W1485456429 hasAuthorship W1485456429A5058511529 @default.
- W1485456429 hasAuthorship W1485456429A5061263756 @default.
- W1485456429 hasAuthorship W1485456429A5074749823 @default.
- W1485456429 hasAuthorship W1485456429A5090824996 @default.
- W1485456429 hasConcept C126322002 @default.
- W1485456429 hasConcept C134018914 @default.
- W1485456429 hasConcept C2777180221 @default.
- W1485456429 hasConcept C2777391703 @default.
- W1485456429 hasConcept C2778163477 @default.
- W1485456429 hasConcept C2779306644 @default.
- W1485456429 hasConcept C2780072125 @default.
- W1485456429 hasConcept C2911022245 @default.
- W1485456429 hasConcept C555293320 @default.
- W1485456429 hasConcept C71924100 @default.
- W1485456429 hasConcept C8243546 @default.
- W1485456429 hasConceptScore W1485456429C126322002 @default.
- W1485456429 hasConceptScore W1485456429C134018914 @default.
- W1485456429 hasConceptScore W1485456429C2777180221 @default.
- W1485456429 hasConceptScore W1485456429C2777391703 @default.
- W1485456429 hasConceptScore W1485456429C2778163477 @default.
- W1485456429 hasConceptScore W1485456429C2779306644 @default.
- W1485456429 hasConceptScore W1485456429C2780072125 @default.
- W1485456429 hasConceptScore W1485456429C2911022245 @default.
- W1485456429 hasConceptScore W1485456429C555293320 @default.
- W1485456429 hasConceptScore W1485456429C71924100 @default.
- W1485456429 hasConceptScore W1485456429C8243546 @default.
- W1485456429 hasIssue "suppl_1" @default.
- W1485456429 hasLocation W14854564291 @default.
- W1485456429 hasOpenAccess W1485456429 @default.
- W1485456429 hasPrimaryLocation W14854564291 @default.
- W1485456429 hasRelatedWork W1969377903 @default.
- W1485456429 hasRelatedWork W1976388697 @default.
- W1485456429 hasRelatedWork W1984065489 @default.
- W1485456429 hasRelatedWork W1987111269 @default.
- W1485456429 hasRelatedWork W2010041847 @default.
- W1485456429 hasRelatedWork W2042930975 @default.
- W1485456429 hasRelatedWork W2087180701 @default.
- W1485456429 hasRelatedWork W2188476519 @default.
- W1485456429 hasRelatedWork W2336832032 @default.
- W1485456429 hasRelatedWork W2380998818 @default.
- W1485456429 hasRelatedWork W2751309050 @default.
- W1485456429 hasRelatedWork W2772113595 @default.
- W1485456429 hasRelatedWork W2801426405 @default.
- W1485456429 hasRelatedWork W2890546355 @default.
- W1485456429 hasRelatedWork W2965691581 @default.
- W1485456429 hasRelatedWork W3011777303 @default.
- W1485456429 hasRelatedWork W3112529462 @default.
- W1485456429 hasRelatedWork W3148502472 @default.
- W1485456429 hasRelatedWork W315253489 @default.
- W1485456429 hasRelatedWork W199774941 @default.
- W1485456429 hasVolume "129" @default.
- W1485456429 isParatext "false" @default.
- W1485456429 isRetracted "false" @default.
- W1485456429 magId "1485456429" @default.
- W1485456429 workType "article" @default.