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- W1485540123 abstract "We have characterized cells from an AIDS-associated non-Hodgkin's lymphoma (NHL). We found a malignant CD5+ B cell (approximately three-fourths of cells), with the balance of cells comprised of T cells having an activated phenotype. The lymphoma was unusual, in that all cells bear T-lineage markers, CD3 and CD5, and B-lineage markers, CD19 and CD20. Thus, conventional immunohistologic techniques were insufficient to type this mixture of cells; single-cell analysis was required. These mixed-phenotype lymphomas may occur frequently in AIDS-associated NHL. Our results show striking similarity to those obtained in the analysis of certain murine CD5+ B-cell lymphomas, suggesting that the study of lymphomagenesis in the mouse may aid in the understanding of AIDS-associated NHL." @default.
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- W1485540123 date "1992-05-01" @default.
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- W1485540123 title "Large-Cell “Mixed-Phenotype” Lymphoma in AIDS" @default.
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- W1485540123 doi "https://doi.org/10.1111/j.1749-6632.1992.tb24641.x" @default.
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