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- W1486052912 abstract "Affinity-purified polyclonal antibodies directed against human lymphoblastoid interferon (IFN), Escherichia coli-derived human IFN-alpha 2, or two synthetic fragments of human IFN-alpha 1 all neutralized the antiviral activity of human alpha IFNs when added to the culture medium of MDBK cells together with IFNs. However, when these antibodies were microinjected into the cytoplasm or the nucleus of cells, subsequent treatment of the cells with IFNs induced full protection against vesicular stomatitis virus. This suggests that IFNs themselves need not act in the cytoplasmic compartment or the nucleus to induce an antiviral state." @default.
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- W1486052912 date "1984-10-01" @default.
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- W1486052912 title "Microinjection of anti-interferon antibodies into cells does not inhibit the induction of an antiviral state by interferon" @default.
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- W1486052912 doi "https://doi.org/10.1128/jvi.52.1.284-287.1984" @default.
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