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- W148627720 abstract "The base-pair parameters wedge-tilt and wedge-roll are extremely useful for describing curved DNA structures. The wedge effect has generally been assumed to be due to the differences between the base-pair tilts and rolls of two successive base-pairs in a DNA molecule. A mathematical formalism has been established here, which shows that, wedgc-roll is a function of basepair tilt and helical twist, similarly the wedge-tilt is a function of base-pair roll and helical twist. This provides a straightforward explanation for the reported wedge-roll in A-DNA helical model of $12^0$ and gives a value of $-3.8^0$ for B-DNA fiber model. The wedge-rolls and wedgetilts calculated for the oligonucleotide crystal structures, using these relations, are in excellent agreement with the values reported earlier, which were .calculated directly from the coordinates, using a global helix axis." @default.
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- W148627720 date "1988-11-05" @default.
- W148627720 modified "2023-09-26" @default.
- W148627720 title "Why do DNA helical models exhibit wedge rolls? A mathematical rationale" @default.
- W148627720 hasPublicationYear "1988" @default.
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