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• W1486361715 endingPage "212" @default.
• W1486361715 startingPage "197" @default.
• W1486361715 abstract "The most common agents of fungal infections include Candida, Cryptococcus, and Aspergillus, since these are ubiquitous and commensal fungal colonizers. This chapter focuses on the treatment of these three important fungal diseases, with an emphasis on Candida. However, the effectiveness of these therapies against other fungal infections also needs to be considered. Currently available antifungal drugs can be grouped into four main categories-polyenes, nucleic acid synthesis inhibitors, ergosterol biosynthesis inhibitors (EBI), and echinocandins. The polyenes are a class of compounds with an amphipathic nature. The echinocandin caspofungin has only recently become clinically available, and so the number of strains with caspofungin resistance, with or without cross-resistance to other echinocandins, is limited. The chapter summarizes the current knowledge about the regulation of resistance in C. albicans sand in other yeast species. In addition to the antifungal drug resistance function of CaMDR1, the other genes have oxidoreductive functions (GRP2 and IFD5) or are potentially involved in pyridoxine (vitamin B6) synthesis (IPF5987 and SNZ1). One of the most important host factors in treating a fungal infection is the patient’s compliance with the drug regimen. Resistance to antifungal drugs has been observed with the azoles and with 5FC. The molecular mechanisms of resistance of C. albicans to azole drugs, including alterations in the target enzyme and in drug efflux pumps, have been well defined." @default.
• W1486361715 created "2016-06-24" @default.
• W1486361715 creator A5007353986 @default.
• W1486361715 creator A5062637687 @default.
• W1486361715 date "2014-04-08" @default.
• W1486361715 modified "2023-09-24" @default.
• W1486361715 title "Molecular Principles of Antifungal Drug Resistance" @default.
• W1486361715 cites W1499627975 @default.
• W1486361715 cites W1523804360 @default.
• W1486361715 cites W1548439859 @default.
• W1486361715 cites W1556261571 @default.
• W1486361715 cites W1573671038 @default.
• W1486361715 cites W1595790960 @default.
• W1486361715 cites W1687425191 @default.
• W1486361715 cites W1811620027 @default.
• W1486361715 cites W1832945357 @default.
• W1486361715 cites W1905535572 @default.
• W1486361715 cites W1906221324 @default.
• W1486361715 cites W1968208372 @default.
• W1486361715 cites W1976277865 @default.
• W1486361715 cites W1983183777 @default.
• W1486361715 cites W1990150397 @default.
• W1486361715 cites W1992992274 @default.
• W1486361715 cites W2000804360 @default.
• W1486361715 cites W2001572899 @default.
• W1486361715 cites W2002933410 @default.
• W1486361715 cites W2003829155 @default.
• W1486361715 cites W2004798418 @default.
• W1486361715 cites W2011401590 @default.
• W1486361715 cites W2021890674 @default.
• W1486361715 cites W2022578647 @default.
• W1486361715 cites W2039999119 @default.
• W1486361715 cites W2041086696 @default.
• W1486361715 cites W2048411015 @default.
• W1486361715 cites W2050080237 @default.
• W1486361715 cites W2053731121 @default.
• W1486361715 cites W2055929620 @default.
• W1486361715 cites W2064775410 @default.
• W1486361715 cites W2072426752 @default.
• W1486361715 cites W2080315399 @default.
• W1486361715 cites W2081628414 @default.
• W1486361715 cites W2085731811 @default.
• W1486361715 cites W2091136135 @default.
• W1486361715 cites W2092009348 @default.
• W1486361715 cites W2097149581 @default.
• W1486361715 cites W2097302864 @default.
• W1486361715 cites W2098169836 @default.
• W1486361715 cites W2098563304 @default.
• W1486361715 cites W2099230922 @default.
• W1486361715 cites W2099282704 @default.
• W1486361715 cites W2099816638 @default.
• W1486361715 cites W2101244261 @default.
• W1486361715 cites W2101712227 @default.
• W1486361715 cites W2101948956 @default.
• W1486361715 cites W2102230982 @default.
• W1486361715 cites W2102541629 @default.
• W1486361715 cites W2103805019 @default.
• W1486361715 cites W2104107099 @default.
• W1486361715 cites W2105638437 @default.
• W1486361715 cites W2107013040 @default.
• W1486361715 cites W2107043911 @default.
• W1486361715 cites W2112458089 @default.
• W1486361715 cites W2115110891 @default.
• W1486361715 cites W2115130703 @default.
• W1486361715 cites W2115172705 @default.
• W1486361715 cites W2116577818 @default.
• W1486361715 cites W2117461892 @default.
• W1486361715 cites W2118836068 @default.
• W1486361715 cites W2120849142 @default.
• W1486361715 cites W2121696857 @default.
• W1486361715 cites W2121972996 @default.
• W1486361715 cites W2123999692 @default.
• W1486361715 cites W2124393272 @default.
• W1486361715 cites W2125056807 @default.
• W1486361715 cites W2125270417 @default.
• W1486361715 cites W2127160528 @default.
• W1486361715 cites W2130969207 @default.
• W1486361715 cites W2131106578 @default.
• W1486361715 cites W2133932584 @default.
• W1486361715 cites W2135536120 @default.
• W1486361715 cites W2136881626 @default.
• W1486361715 cites W2140701924 @default.
• W1486361715 cites W2140936126 @default.
• W1486361715 cites W2141048809 @default.
• W1486361715 cites W2141175322 @default.
• W1486361715 cites W2141401951 @default.
• W1486361715 cites W2142427146 @default.
• W1486361715 cites W2142859033 @default.
• W1486361715 cites W2143401680 @default.
• W1486361715 cites W2145439495 @default.
• W1486361715 cites W2147757952 @default.
• W1486361715 cites W2148266917 @default.
• W1486361715 cites W2148652865 @default.
• W1486361715 cites W2149198831 @default.
• W1486361715 cites W2150140261 @default.
• W1486361715 cites W2152302945 @default.
• W1486361715 cites W2158859009 @default.
• W1486361715 cites W2160765565 @default.

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