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- W1486702970 abstract "Young adult RF male mice were injected intravenously with radioactive strontium as followsn Group l, 0.2 Vc Sr/sup 90/g after splenectomy; Group II, 0.2 mu c Sr/sup 90/g after sham splenectomy; Group III, 0.51 gamma c Sr/sup 89// g; Group IV, 0.04 mu c Sr/sup 90//g; and Group V, uninjected controls. After injection, the mice were observed until death, and effects on the life span and incidence of neoplastic and norneoplastic diseases were studied. A dose of 0.2 mu c Sr/sup 90//g, with or without splenectomy, increased the incidence of thymic lymphosarcoma but did not detectably alter the incidence of myeloid leukemia. Other leukemias and lymphomas were also increased in number and occurred earlier. Two malignant bone tumors were found in 102 animals receiving 0.2 mu c Sr/sup 90//g, and one in 75 animals receiving 0.04 mu c Sr/sup 90//g, while none were noted in controls or in animals receiving 0.51 mu c Sr/sup 89//g. Effects on the life span were variable and of equivocal biological significance. (auth)" @default.
- W1486702970 created "2016-06-24" @default.
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- W1486702970 date "1962-07-01" @default.
- W1486702970 modified "2023-09-23" @default.
- W1486702970 title "Some late effects of radiostrontium in RF male mice." @default.
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