Matches in SemOpenAlex for { <https://semopenalex.org/work/W1486725311> ?p ?o ?g. }
- W1486725311 endingPage "4869" @default.
- W1486725311 startingPage "4861" @default.
- W1486725311 abstract "The expression of the major vegetative phase-specific autolysin genes (cwlB [lytC] and cwlG [lytD]) was greatly reduced by mecA and mecB null mutations. In contrast to the negative effects on late competence genes (such as comG) and levansucrase gene (sacB) expression, this positive effect of mec genes on autolysin gene expression was not mediated through the ComK protein but apparently through the level of the SigD protein. The pleiotropic effects of the mec mutations, i.e., the reduction of sigD expression and the overexpression of the ComK protein, seem not to be interwoven since the SigD- and ComK-dependent functions are clearly separable in the mec mutants. We also show that the synthesis of the flagellin protein, which is encoded by the SigD-dependent hag gene, was similarly affected by the mec mutations. Complementation analysis with a SigD-overproducing plasmid, pHYSigD, in mec mutants revealed the reversion of almost all of the SigD-dependent phenotypes except motility. This finding suggested that Mec proteins act on motility genes at two levels, one of which is apparently SigD independent. Finally, we discuss the transcriptional regulation of the sigD gene by multiple regulators, i.e., MecA, MecB, SinR (FlaD), and DegS-DegU, and its implications for cells in a global context." @default.
- W1486725311 created "2016-06-24" @default.
- W1486725311 creator A5021944442 @default.
- W1486725311 creator A5042960304 @default.
- W1486725311 creator A5048290923 @default.
- W1486725311 date "1996-08-01" @default.
- W1486725311 modified "2023-09-27" @default.
- W1486725311 title "Effects of mecA and mecB (clpC) mutations on expression of sigD, which encodes an alternative sigma factor, and autolysin operons and on flagellin synthesis in Bacillus subtilis" @default.
- W1486725311 cites W1141782513 @default.
- W1486725311 cites W1505519692 @default.
- W1486725311 cites W1521877748 @default.
- W1486725311 cites W1529324281 @default.
- W1486725311 cites W1554639867 @default.
- W1486725311 cites W1572746801 @default.
- W1486725311 cites W1578015507 @default.
- W1486725311 cites W1678194650 @default.
- W1486725311 cites W1823447345 @default.
- W1486725311 cites W1853627239 @default.
- W1486725311 cites W1856112995 @default.
- W1486725311 cites W1867480659 @default.
- W1486725311 cites W1901538719 @default.
- W1486725311 cites W1903519221 @default.
- W1486725311 cites W1926048579 @default.
- W1486725311 cites W1957834460 @default.
- W1486725311 cites W1969766795 @default.
- W1486725311 cites W1971562545 @default.
- W1486725311 cites W1994515479 @default.
- W1486725311 cites W2000528491 @default.
- W1486725311 cites W2014089642 @default.
- W1486725311 cites W2018289835 @default.
- W1486725311 cites W2030360373 @default.
- W1486725311 cites W2036659415 @default.
- W1486725311 cites W2073894003 @default.
- W1486725311 cites W2092189990 @default.
- W1486725311 cites W2100521476 @default.
- W1486725311 cites W2100837269 @default.
- W1486725311 cites W2108067686 @default.
- W1486725311 cites W2111530819 @default.
- W1486725311 cites W2122170001 @default.
- W1486725311 cites W2124329426 @default.
- W1486725311 cites W2125403249 @default.
- W1486725311 cites W2128830783 @default.
- W1486725311 cites W2132032473 @default.
- W1486725311 cites W2134746740 @default.
- W1486725311 cites W2145047081 @default.
- W1486725311 cites W2146156845 @default.
- W1486725311 cites W2153797926 @default.
- W1486725311 cites W2163761466 @default.
- W1486725311 cites W2167629962 @default.
- W1486725311 cites W2170103578 @default.
- W1486725311 cites W941443519 @default.
- W1486725311 doi "https://doi.org/10.1128/jb.178.16.4861-4869.1996" @default.
- W1486725311 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/178268" @default.
- W1486725311 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8759849" @default.
- W1486725311 hasPublicationYear "1996" @default.
- W1486725311 type Work @default.
- W1486725311 sameAs 1486725311 @default.
- W1486725311 citedByCount "26" @default.
- W1486725311 countsByYear W14867253112013 @default.
- W1486725311 countsByYear W14867253112014 @default.
- W1486725311 countsByYear W14867253112015 @default.
- W1486725311 countsByYear W14867253112016 @default.
- W1486725311 countsByYear W14867253112017 @default.
- W1486725311 countsByYear W14867253112018 @default.
- W1486725311 crossrefType "journal-article" @default.
- W1486725311 hasAuthorship W1486725311A5021944442 @default.
- W1486725311 hasAuthorship W1486725311A5042960304 @default.
- W1486725311 hasAuthorship W1486725311A5048290923 @default.
- W1486725311 hasBestOaLocation W14867253112 @default.
- W1486725311 hasConcept C104317684 @default.
- W1486725311 hasConcept C143065580 @default.
- W1486725311 hasConcept C188082640 @default.
- W1486725311 hasConcept C203075996 @default.
- W1486725311 hasConcept C2776809874 @default.
- W1486725311 hasConcept C38117629 @default.
- W1486725311 hasConcept C54355233 @default.
- W1486725311 hasConcept C86803240 @default.
- W1486725311 hasConceptScore W1486725311C104317684 @default.
- W1486725311 hasConceptScore W1486725311C143065580 @default.
- W1486725311 hasConceptScore W1486725311C188082640 @default.
- W1486725311 hasConceptScore W1486725311C203075996 @default.
- W1486725311 hasConceptScore W1486725311C2776809874 @default.
- W1486725311 hasConceptScore W1486725311C38117629 @default.
- W1486725311 hasConceptScore W1486725311C54355233 @default.
- W1486725311 hasConceptScore W1486725311C86803240 @default.
- W1486725311 hasIssue "16" @default.
- W1486725311 hasLocation W14867253111 @default.
- W1486725311 hasLocation W14867253112 @default.
- W1486725311 hasLocation W14867253113 @default.
- W1486725311 hasLocation W14867253114 @default.
- W1486725311 hasOpenAccess W1486725311 @default.
- W1486725311 hasPrimaryLocation W14867253111 @default.
- W1486725311 hasRelatedWork W1507023994 @default.
- W1486725311 hasRelatedWork W1519902998 @default.
- W1486725311 hasRelatedWork W1760488055 @default.
- W1486725311 hasRelatedWork W2117110650 @default.
- W1486725311 hasRelatedWork W2128665526 @default.
- W1486725311 hasRelatedWork W2144490660 @default.