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• W1487075060 abstract "We conducted a comparative clinical study to evaluate the prophylactic effects of micafungin (MCFG) and fluconazole (FLCZ) on the incidence of fungal infections in extremely low-birthweight infants who were born at a gestational age of less than 26 weeks and weighed less than 1000 g.With a combination of enteral administration of miconazole (6 mg/kg/day), FLCZ and MCFG were administered intravenously at a dose of 5 mg/kg/day and 3 mg/kg/day, respectively. The prophylaxis was classified as a failure when fungal infections were identified within the first 21 days after birth.The prophylaxis was successful in seven of 18 cases (39%) in the FLCZ group and 15 of 21 cases (71%) in the MCFG group, indicating that the success rate was significantly higher in the latter group.MCFG was superior to FLCZ as prophylaxis against fungal infections in extremely low-birthweight infants." @default.
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• W1487075060 date "2013-08-21" @default.
• W1487075060 modified "2023-10-02" @default.
• W1487075060 title "Micafungin versus fluconazole for prophylaxis against fungal infections in premature infants" @default.
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• W1487075060 doi "https://doi.org/10.1111/ped.12157" @default.
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