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• W1487241221 endingPage "74" @default.
• W1487241221 startingPage "48" @default.
• W1487241221 abstract "RNA World research in recent years has sought to establish whether ribozymes have the catalytic versatility and potency to transmit genetic information and to sustain a credible metabolism. At a minimum, organisms from just before the Protein Revolution would have had to catalyze nucleotide polymerization and invent the machinery for protein synthesis. There are now RNA enzymes (ribozymes) that catalyze the individual steps in each of these reactions. Some of the current challenges include increasing the vigor with which the individual reactions are catalyzed, strengthening the affinity and specificity of substrate recognition, integrating ribozymes into metabolic paths and coordinated networks of linked reactions, and deriving a ribozyme-catalyzed metabolic context to sustain the core reactions." @default.
• W1487241221 created "2016-06-24" @default.
• W1487241221 creator A5018442903 @default.
• W1487241221 date "2004-01-01" @default.
• W1487241221 modified "2023-10-12" @default.
• W1487241221 title "Ribozyme-Catalyzed Genetics" @default.
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