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- W1487309080 abstract "Today, machines turn out the sequence of a million DNA bases in a day. Fifty years ago, when the chemical and biochemical tools for studying DNA and RNA were at best rudimentary, such a machine was unimaginable. Then, the cutting edge was Erwin Chargaff's demonstration, in 1948, that the base composition of DNA could be reliably determined. His discovery that all DNAs contain equal amounts of adenine and thymine and similarly of guanine and cytosine depended on applying two recent developments: partition chromatography and the absorption spectra of nucleic acid constituents." @default.
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- W1487309080 date "2003-11-01" @default.
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- W1487309080 title "Leon Heppel and the Early Days of RNA Biochemistry" @default.
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- W1487309080 doi "https://doi.org/10.1074/jbc.x300008200" @default.
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