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• W1487414386 abstract "Alcohol use is one of the most prominent causes of dyslipidemia. The effects of alcohol on lipid metabolism are diverse: it induces synthesis of triglycerides, formation of very low density cholesterol and stimulates lipolysis in fatty tissue. HIV infection also predisposes to lipid disturbances resulting from direct influence of the virus as well as from the action of antiretroviral drugs, however coinfection with HCV is considered to be protective against significant dyslipidemia in some cases. Hypertriglyceridemia is a risk factor of cardiovascular disease and severe form is considered to be at increased risk for acute pancreatitis. 36-years old HIV/HCV coinfected patient was diagnosed with severe hypertriglyceridemia exciding 8000 mg/dL. Periodic alcohol abuse was stated. Fenofibrate initiation and antiretroviral therapy switch did not influence the lipid levels significantly. Increase in lipids levels occurred simultaneously with periods of alcohol abuse. In conclusion, HIV/HCV coinfection does not seem to influence severe dyslipidemia induced by alcohol use." @default.
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• W1487414386 date "2014-05-12" @default.
• W1487414386 modified "2023-09-26" @default.
• W1487414386 title "Alcohol induced severe hypertriglyceridemia in HIV/HCV coinfected patient – case report" @default.
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