FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1488404820> ?p ?o ?g. }

• W1488404820 endingPage "1158" @default.
• W1488404820 startingPage "1158" @default.
• W1488404820 abstract "Angioedema is an episodic disorder caused by increased capillary permeability that results in extravasation of intravascular fluid and angioedematous swellings. The disorder can affect the face, upper airways, gastrointestinal tract, genital area and limbs. Life-threatening presentations include airways obstruction and hypovolemic shock. In the majority of patients, angioedema is either idiopathic or weakly related to exposure to allergens. The latter can include allergic reactions to foods and adverse responses to drugs such as angiotensin-converting enzyme inhibitors. Hereditary angioedema is associated with abnormalities of complement, usually a deficiency of C1 inhibitor. The symptoms of angioedema of the small bowel include abdominal pain, nausea and vomiting. Pathologically, the small bowel wall becomes thick and edematous. Typical changes on a contrast-enhanced computed tomography (CT) scan include a thick small bowel wall, low attenuation of the edematous submucosa and enhancement of a thickened mucosa and serosa. These changes can be segmental or diffuse and are usually associated with fluid distension of the small bowel. The radiological appearance is similar to that of intestinal vasculitis. Other differential diagnoses include bowel ischemia, intramural bleeding, nephrotic syndrome, infections and inflammatory bowel disease. The images shown below were from two different patients with angioedema. The CT scan in Figure 1 shows striking edema of the small bowel wall, enhancement of the mucosa and serosa and fluid accumulation in the bowel lumen. The patient was a 33-year-old woman who was admitted to hospital with abdominal pain, nausea and vomiting. Serum complement studies revealed normal C1-esterase inhibitor functional activity but low levels of C3 and C4. Two years later, she was diagnosed with systemic lupus erythematosus, a disorder that is commonly associated with complement deficiencies. The CT scan in Figure 2 also shows dilatation and thickening of small bowel loops with clear delineation of layers of the small bowel wall. The patient was a 37-year-old man who was admitted to hospital with abdominal pain and facial edema, particularly around the mouth. The episode of angioedema was unexplained although he was known to have atopic dermatitis. Both patients gradually improved with analgesics and intravenous fluids. Subsequently, they were treated with tranexamic acid and d-chlorpheniramine maleate, although neither drug has been evaluated in randomized trials. Contributed by" @default.
• W1488404820 created "2016-06-24" @default.
• W1488404820 creator A5056531353 @default.
• W1488404820 creator A5057972733 @default.
• W1488404820 creator A5065295892 @default.
• W1488404820 creator A5069753860 @default.
• W1488404820 creator A5084338218 @default.
• W1488404820 date "2008-07-01" @default.
• W1488404820 modified "2023-10-16" @default.
• W1488404820 title "Gastrointestinal: Angioedema of the small bowel" @default.
• W1488404820 doi "https://doi.org/10.1111/j.1440-1746.2008.05491.x" @default.
• W1488404820 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18707600" @default.
• W1488404820 hasPublicationYear "2008" @default.
• W1488404820 type Work @default.
• W1488404820 sameAs 1488404820 @default.
• W1488404820 citedByCount "1" @default.
• W1488404820 crossrefType "journal-article" @default.
• W1488404820 hasAuthorship W1488404820A5056531353 @default.
• W1488404820 hasAuthorship W1488404820A5057972733 @default.
• W1488404820 hasAuthorship W1488404820A5065295892 @default.
• W1488404820 hasAuthorship W1488404820A5069753860 @default.
• W1488404820 hasAuthorship W1488404820A5084338218 @default.
• W1488404820 hasConcept C126322002 @default.
• W1488404820 hasConcept C142724271 @default.
• W1488404820 hasConcept C2777995640 @default.
• W1488404820 hasConcept C2780580376 @default.
• W1488404820 hasConcept C2780852908 @default.
• W1488404820 hasConcept C2780886150 @default.
• W1488404820 hasConcept C2780955771 @default.
• W1488404820 hasConcept C71924100 @default.
• W1488404820 hasConcept C90924648 @default.
• W1488404820 hasConceptScore W1488404820C126322002 @default.
• W1488404820 hasConceptScore W1488404820C142724271 @default.
• W1488404820 hasConceptScore W1488404820C2777995640 @default.
• W1488404820 hasConceptScore W1488404820C2780580376 @default.
• W1488404820 hasConceptScore W1488404820C2780852908 @default.
• W1488404820 hasConceptScore W1488404820C2780886150 @default.
• W1488404820 hasConceptScore W1488404820C2780955771 @default.
• W1488404820 hasConceptScore W1488404820C71924100 @default.
• W1488404820 hasConceptScore W1488404820C90924648 @default.
• W1488404820 hasIssue "7pt1" @default.
• W1488404820 hasLocation W14884048201 @default.
• W1488404820 hasLocation W14884048202 @default.
• W1488404820 hasOpenAccess W1488404820 @default.
• W1488404820 hasPrimaryLocation W14884048201 @default.
• W1488404820 hasRelatedWork W2000953087 @default.
• W1488404820 hasRelatedWork W2034503533 @default.
• W1488404820 hasRelatedWork W2320562621 @default.
• W1488404820 hasRelatedWork W2387364079 @default.
• W1488404820 hasRelatedWork W2415235027 @default.
• W1488404820 hasRelatedWork W26594511 @default.
• W1488404820 hasRelatedWork W3048457546 @default.
• W1488404820 hasRelatedWork W3142684436 @default.
• W1488404820 hasRelatedWork W4242805581 @default.
• W1488404820 hasRelatedWork W50187013 @default.
• W1488404820 hasVolume "23" @default.
• W1488404820 isParatext "false" @default.
• W1488404820 isRetracted "false" @default.
• W1488404820 magId "1488404820" @default.
• W1488404820 workType "article" @default.