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- W1488679181 abstract "Publisher Summary This chapter introduces the techniques of intravital microscopy as a tool to study the microcirculation in intact animals under conditions of oxidative stress. Intravital fluorescence microscopy can be performed with almost all types of epiillumination microscopes available. The introduction of fluorescent dyes and refined epiillumination techniques has significantly advanced the possibilities of intravital microscopic studies of the liver microcirculation, including quantitative analyses of both circulatory parameters and cellular mechanisms. Using appropriate dyes, intravital microscopy allows the study of (1) microvascular perfusion, (2) leukocyte-endothelial cell interaction, (3) Kupffer cell and Ito cell function, and (4) hepatocellular membrane damage and mitochondrial redox state. The chapter discusses the role of reactive oxygen species (ROS) in hepatic microcirculatory dysfunction." @default.
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- W1488679181 date "1999-01-01" @default.
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- W1488679181 title "Intravital fluorescence microscopy for the study of leukocyte interaction with platelets and endothelial cells" @default.
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- W1488679181 doi "https://doi.org/10.1016/s0076-6879(99)00151-2" @default.
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