FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1488696575> ?p ?o ?g. }

• W1488696575 endingPage "134" @default.
• W1488696575 startingPage "128" @default.
• W1488696575 abstract "Interleukin-11 (IL-11) is a bone marrow microenvironment-derived growth factor with pleiotropic effects on a variety of hematopoietic cells. To more accurately assess the effects of IL-11 on stem and progenitor compartments within the hematopoietic microenvironment (HM), we added recombinant human (rh) IL-11 to human and murine long-term bone marrow cultures (LTMC) and analyzed primitive (high proliferative potential- colony forming cells [HPP-CFC], long-term culture-initiating cells [LTC- IC], and long-term reconstituting stem cells) and progenitor (day 12 colony forming unit-spleen [CFU-S12], colony forming unit-megakaryocyte [CFU-Mk] and colony forming unit-granulocyte/macrophage [CFU-GM]) compartments throughout the duration of the cultures. rhIL-11 (100 ng/mL) added twice weekly resulted in significantly increased nonadherent (NA) cellularity, CFU-GM, and CFU-Mk production in human LTMC. Addition of rhIL-11 to murine LTMC was associated with a 5- to 40- fold increase in CFU-GM and a four- to 20-fold increase in day 12 CFU-S in NA cells. However, IL-11 had no significant effect on total HPP-CFC concentration and decreased the size of the more primitive stem/progenitor compartment as evidenced by both decreased LTC-IC frequency in human LTMC and decreased frequency of long-term reconstituting stem cells in murine LTMC. These data suggest that IL-11 may increase commitment of stem cells into a multipotential progenitor compartment." @default.
• W1488696575 created "2016-06-24" @default.
• W1488696575 creator A5016954149 @default.
• W1488696575 creator A5019990477 @default.
• W1488696575 creator A5038432767 @default.
• W1488696575 creator A5072173677 @default.
• W1488696575 creator A5086962161 @default.
• W1488696575 creator A5091776903 @default.
• W1488696575 date "1995-07-01" @default.
• W1488696575 modified "2023-10-06" @default.
• W1488696575 title "Interleukin-11 stimulates multilineage progenitors, but not stem cells, in murine and human long-term marrow cultures" @default.
• W1488696575 cites W1538762819 @default.
• W1488696575 cites W1565389310 @default.
• W1488696575 cites W1572556724 @default.
• W1488696575 cites W1582172850 @default.
• W1488696575 cites W1608210758 @default.
• W1488696575 cites W181178150 @default.
• W1488696575 cites W1976861055 @default.
• W1488696575 cites W1991055608 @default.
• W1488696575 cites W2010576286 @default.
• W1488696575 cites W2016191371 @default.
• W1488696575 cites W2018934530 @default.
• W1488696575 cites W2031179453 @default.
• W1488696575 cites W2086793358 @default.
• W1488696575 cites W2100314915 @default.
• W1488696575 cites W2100461037 @default.
• W1488696575 cites W2104163133 @default.
• W1488696575 cites W2118024162 @default.
• W1488696575 cites W2255087338 @default.
• W1488696575 cites W2298463596 @default.
• W1488696575 cites W2342394157 @default.
• W1488696575 cites W2374798852 @default.
• W1488696575 cites W2394997124 @default.
• W1488696575 cites W2397971170 @default.
• W1488696575 cites W2404888684 @default.
• W1488696575 cites W2407358651 @default.
• W1488696575 cites W2408394722 @default.
• W1488696575 cites W2410840537 @default.
• W1488696575 cites W2415983912 @default.
• W1488696575 cites W2417585448 @default.
• W1488696575 cites W2418420055 @default.
• W1488696575 cites W273564206 @default.
• W1488696575 doi "https://doi.org/10.1182/blood.v86.1.128.bloodjournal861128" @default.
• W1488696575 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7795218" @default.
• W1488696575 hasPublicationYear "1995" @default.
• W1488696575 type Work @default.
• W1488696575 sameAs 1488696575 @default.
• W1488696575 citedByCount "24" @default.
• W1488696575 countsByYear W14886965752017 @default.
• W1488696575 countsByYear W14886965752023 @default.
• W1488696575 crossrefType "journal-article" @default.
• W1488696575 hasAuthorship W1488696575A5016954149 @default.
• W1488696575 hasAuthorship W1488696575A5019990477 @default.
• W1488696575 hasAuthorship W1488696575A5038432767 @default.
• W1488696575 hasAuthorship W1488696575A5072173677 @default.
• W1488696575 hasAuthorship W1488696575A5086962161 @default.
• W1488696575 hasAuthorship W1488696575A5091776903 @default.
• W1488696575 hasBestOaLocation W14886965751 @default.
• W1488696575 hasConcept C109159458 @default.
• W1488696575 hasConcept C131665280 @default.
• W1488696575 hasConcept C153911025 @default.
• W1488696575 hasConcept C192285135 @default.
• W1488696575 hasConcept C201750760 @default.
• W1488696575 hasConcept C2022786 @default.
• W1488696575 hasConcept C203014093 @default.
• W1488696575 hasConcept C2776090121 @default.
• W1488696575 hasConcept C2779705218 @default.
• W1488696575 hasConcept C2780007613 @default.
• W1488696575 hasConcept C28328180 @default.
• W1488696575 hasConcept C523546767 @default.
• W1488696575 hasConcept C54355233 @default.
• W1488696575 hasConcept C67662055 @default.
• W1488696575 hasConcept C86803240 @default.
• W1488696575 hasConcept C8891405 @default.
• W1488696575 hasConcept C95444343 @default.
• W1488696575 hasConceptScore W1488696575C109159458 @default.
• W1488696575 hasConceptScore W1488696575C131665280 @default.
• W1488696575 hasConceptScore W1488696575C153911025 @default.
• W1488696575 hasConceptScore W1488696575C192285135 @default.
• W1488696575 hasConceptScore W1488696575C201750760 @default.
• W1488696575 hasConceptScore W1488696575C2022786 @default.
• W1488696575 hasConceptScore W1488696575C203014093 @default.
• W1488696575 hasConceptScore W1488696575C2776090121 @default.
• W1488696575 hasConceptScore W1488696575C2779705218 @default.
• W1488696575 hasConceptScore W1488696575C2780007613 @default.
• W1488696575 hasConceptScore W1488696575C28328180 @default.
• W1488696575 hasConceptScore W1488696575C523546767 @default.
• W1488696575 hasConceptScore W1488696575C54355233 @default.
• W1488696575 hasConceptScore W1488696575C67662055 @default.
• W1488696575 hasConceptScore W1488696575C86803240 @default.
• W1488696575 hasConceptScore W1488696575C8891405 @default.
• W1488696575 hasConceptScore W1488696575C95444343 @default.
• W1488696575 hasIssue "1" @default.
• W1488696575 hasLocation W14886965751 @default.
• W1488696575 hasOpenAccess W1488696575 @default.
• W1488696575 hasPrimaryLocation W14886965751 @default.
• W1488696575 hasRelatedWork W1974516599 @default.
• W1488696575 hasRelatedWork W2026277165 @default.

• next