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- W1488896078 abstract "A summary is presented on the development of a specific gene mutation assay, the Chinese hamster ovary cells/hypoxanthine-guanine phosphoribosyl transferase (CHO/HGPRT) system, and the utilization of this system to study structure-activity relationship affecting cytotoxicity and gene mutation by various carcinogens. Then, preliminary development and validation of a Multiplex CHO System for the simultaneous determination of chromosome aberration, sister chromatid exchange in addition to cytotoxicity and gene mutation is presented. The potential use of a CHO/human cell hybrid system for measuring chromosomal deletion and loss is discussed." @default.
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- W1488896078 date "1980-01-01" @default.
- W1488896078 modified "2023-09-24" @default.
- W1488896078 title "Quantitative mutagenesis and mutagen screening with Chinese hamster ovary cells" @default.
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