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• W1489046562 startingPage "11" @default.
• W1489046562 abstract "Interpretation of exploding knowledge about Barrett's esophagus is impaired by use of several conflicting definitions. Because any histological type of esophageal columnar metaplasia carries risk for esophageal adenocarcinoma, the diagnosis of Barrett's esophagus should no longer require demonstration of intestinal-type metaplasia. Endoscopic recognition and grading of Barrett's esophagus remains a significant source of ambiguity. Reflux disease is a key factor for development of Barrett's esophagus, but other factors must underlie its development, since it occurs in only a minority of reflux disease patients. Neither antireflux surgery nor proton pump inhibitor (PPI) therapy has major impacts on cancer risk. Within a year, a major trial should indicate whether low-dose aspirin usefully reduces cancer risk. The best referral centers have transformed the accuracy of screening and surveillance for early curable esophageal adenocarcinoma by use of enhanced and novel endoscopic imaging, visually-guided, rather than blind biopsies and by partnership with expert pathologists. General endoscopists now need to upgrade their skills and equipment so that they can rely mainly on visual targeting of biopsies on mucosal areas of concern in their surveillance practice. General pathologists need to greatly improve their interpretation of biopsies. Endoscopic therapy now achieves very high rates of cure of high-grade dysplasia and esophageal adenocarcinoma with minimal morbidity and risk. Such results will only be achieved by skilled interventional endoscopists. Esophagectomy should now be mainly restricted to patients whose cancer has extended into and beyond the submucosa. Weighing risks and benefits in the management of Barrett's esophagus is difficult, as is the process of adequately informing patients about their specific cancer risk." @default.
• W1489046562 created "2016-06-24" @default.
• W1489046562 creator A5060346124 @default.
• W1489046562 date "2011-01-01" @default.
• W1489046562 modified "2023-10-18" @default.
• W1489046562 title "Barrett's esophagus: A historical perspective, an update on core practicalities and predictions on future evolutions of management" @default.
• W1489046562 cites W1513308932 @default.
• W1489046562 cites W1963825561 @default.
• W1489046562 cites W1964803683 @default.
• W1489046562 cites W1966873535 @default.
• W1489046562 cites W1978569786 @default.
• W1489046562 cites W1979250736 @default.
• W1489046562 cites W1981712981 @default.
• W1489046562 cites W1982397085 @default.
• W1489046562 cites W1984060133 @default.
• W1489046562 cites W1985822229 @default.
• W1489046562 cites W1987672679 @default.
• W1489046562 cites W1988935165 @default.
• W1489046562 cites W1990750850 @default.
• W1489046562 cites W1991195448 @default.
• W1489046562 cites W1992180749 @default.
• W1489046562 cites W1993228606 @default.
• W1489046562 cites W1996674377 @default.
• W1489046562 cites W1998821113 @default.
• W1489046562 cites W1998897263 @default.
• W1489046562 cites W1999387186 @default.
• W1489046562 cites W2001581777 @default.
• W1489046562 cites W2002800925 @default.
• W1489046562 cites W2003201984 @default.
• W1489046562 cites W2007907793 @default.
• W1489046562 cites W2008628923 @default.
• W1489046562 cites W2008644165 @default.
• W1489046562 cites W2010403706 @default.
• W1489046562 cites W2010870495 @default.
• W1489046562 cites W2018202257 @default.
• W1489046562 cites W2018405529 @default.
• W1489046562 cites W2018715346 @default.
• W1489046562 cites W2020160547 @default.
• W1489046562 cites W2023798373 @default.
• W1489046562 cites W2024335546 @default.
• W1489046562 cites W2025343608 @default.
• W1489046562 cites W2026891239 @default.
• W1489046562 cites W2027055705 @default.
• W1489046562 cites W2030162709 @default.
• W1489046562 cites W2032345866 @default.
• W1489046562 cites W2032355530 @default.
• W1489046562 cites W2033365771 @default.
• W1489046562 cites W2033652178 @default.
• W1489046562 cites W2034671080 @default.
• W1489046562 cites W2034872216 @default.
• W1489046562 cites W2036194723 @default.
• W1489046562 cites W2036768248 @default.
• W1489046562 cites W2038506721 @default.
• W1489046562 cites W2042159861 @default.
• W1489046562 cites W2045050904 @default.
• W1489046562 cites W2046888456 @default.
• W1489046562 cites W2048143418 @default.
• W1489046562 cites W2049803129 @default.
• W1489046562 cites W2058229283 @default.
• W1489046562 cites W2058924922 @default.
• W1489046562 cites W2058960594 @default.
• W1489046562 cites W2062495464 @default.
• W1489046562 cites W2064545441 @default.
• W1489046562 cites W2065921642 @default.
• W1489046562 cites W2068932720 @default.
• W1489046562 cites W2073736641 @default.
• W1489046562 cites W2076565183 @default.
• W1489046562 cites W2084810416 @default.
• W1489046562 cites W2087237668 @default.
• W1489046562 cites W2087388776 @default.
• W1489046562 cites W2087804429 @default.
• W1489046562 cites W2087963054 @default.
• W1489046562 cites W2091353440 @default.
• W1489046562 cites W2091483584 @default.
• W1489046562 cites W2094005862 @default.
• W1489046562 cites W2098511302 @default.
• W1489046562 cites W2105704329 @default.
• W1489046562 cites W2107114880 @default.
• W1489046562 cites W2108748826 @default.
• W1489046562 cites W2114076424 @default.
• W1489046562 cites W2114442699 @default.
• W1489046562 cites W2114660410 @default.
• W1489046562 cites W2117419667 @default.
• W1489046562 cites W2120339587 @default.
• W1489046562 cites W2120450267 @default.
• W1489046562 cites W2120667716 @default.
• W1489046562 cites W2129241891 @default.
• W1489046562 cites W2130591858 @default.
• W1489046562 cites W2133628870 @default.
• W1489046562 cites W2141147516 @default.
• W1489046562 cites W2149470687 @default.
• W1489046562 cites W2149491624 @default.
• W1489046562 cites W2152173169 @default.
• W1489046562 cites W2156802685 @default.
• W1489046562 cites W2157185759 @default.
• W1489046562 cites W2157842267 @default.
• W1489046562 cites W2166479153 @default.
• W1489046562 cites W2169115304 @default.

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