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• W1489062892 abstract "Abstract The identification of poliovirus receptor‐like 4 ( PVRL4 ) as the second natural receptor for measles virus ( MV ) has closed a major gap in our understanding of measles pathogenesis, and explains how this predominantly lymphotropic virus breaks through epithelial barriers to transmit to a susceptible host. Advances in the development of wild‐type, recombinant MVs which express fluorescent proteins making infected cells readily detectable in living tissues and animals, has also increased our understanding of this important and highly transmissible human disease. Thus, it is timely to review how these advances have provided new insights into MV infection of immune, epithelial and neural cells. This demands access to primate samples that help us understand the early and acute stages of the disease, which are challenging to dissect due to the mild/self‐limiting nature of the infection. It also requires well‐characterized and rather rare human tissue samples from patients who succumb to neurological sequelae to help study the consequences of the long‐term persistence of this RNA virus in vivo . Collectively, these studies have provided unique insights into how the use of two cellular receptors, CD150 and PVRL4 , governs the in vivo tissue‐specific temporal patterns of virus spread and resulting pathological lesions. Analysis of tissue samples has also demonstrated the importance of differing mechanisms of virus cell‐to‐cell spread within lymphoid, epithelial and neural tissues in the dissemination of MV during acute and long‐term persistent infections. Given the incentive to eradicate MV globally, and the inevitable question as to whether or not vaccination should cease in light of the existence of closely related morbilliviruses, a thorough understanding of measles pathological lesions is essential. Copyright © 2014 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd." @default.
• W1489062892 created "2016-06-24" @default.
• W1489062892 creator A5012707353 @default.
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• W1489062892 creator A5048652049 @default.
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• W1489062892 creator A5074409519 @default.
• W1489062892 date "2014-12-11" @default.
• W1489062892 modified "2023-09-26" @default.
• W1489062892 title "Pathological consequences of systemic measles virus infection" @default.
• W1489062892 cites W10201552 @default.
• W1489062892 cites W144673708 @default.
• W1489062892 cites W1483418093 @default.
• W1489062892 cites W1535240987 @default.
• W1489062892 cites W1560910767 @default.
• W1489062892 cites W1579118981 @default.
• W1489062892 cites W1591890160 @default.
• W1489062892 cites W1605916189 @default.
• W1489062892 cites W1645339183 @default.
• W1489062892 cites W1845094941 @default.
• W1489062892 cites W1947526424 @default.
• W1489062892 cites W1965812656 @default.
• W1489062892 cites W1968748213 @default.
• W1489062892 cites W1972431425 @default.
• W1489062892 cites W1972759043 @default.
• W1489062892 cites W1974237253 @default.
• W1489062892 cites W1978452294 @default.
• W1489062892 cites W1980154951 @default.
• W1489062892 cites W1982829132 @default.
• W1489062892 cites W1988519719 @default.
• W1489062892 cites W1989171408 @default.
• W1489062892 cites W1990770553 @default.
• W1489062892 cites W1994648730 @default.
• W1489062892 cites W1995004375 @default.
• W1489062892 cites W1998631409 @default.
• W1489062892 cites W1998716443 @default.
• W1489062892 cites W2001589443 @default.
• W1489062892 cites W2001949677 @default.
• W1489062892 cites W2004791992 @default.
• W1489062892 cites W2012721575 @default.
• W1489062892 cites W2014563507 @default.
• W1489062892 cites W2015093031 @default.
• W1489062892 cites W2015455519 @default.
• W1489062892 cites W2018539079 @default.
• W1489062892 cites W2020622263 @default.
• W1489062892 cites W2021345942 @default.
• W1489062892 cites W2022709261 @default.
• W1489062892 cites W2029280196 @default.
• W1489062892 cites W2031539862 @default.
• W1489062892 cites W2031851377 @default.
• W1489062892 cites W2033091848 @default.
• W1489062892 cites W2037733700 @default.
• W1489062892 cites W2039635444 @default.
• W1489062892 cites W2042288895 @default.
• W1489062892 cites W2044362819 @default.
• W1489062892 cites W2045022648 @default.
• W1489062892 cites W2045307320 @default.
• W1489062892 cites W2046485092 @default.
• W1489062892 cites W2051272451 @default.
• W1489062892 cites W2052653597 @default.
• W1489062892 cites W2058478773 @default.
• W1489062892 cites W2059869414 @default.
• W1489062892 cites W2060638702 @default.
• W1489062892 cites W2063013193 @default.
• W1489062892 cites W2063931926 @default.
• W1489062892 cites W2065178191 @default.
• W1489062892 cites W2065321703 @default.
• W1489062892 cites W2066877940 @default.
• W1489062892 cites W2067270269 @default.
• W1489062892 cites W2067847775 @default.
• W1489062892 cites W2068693682 @default.
• W1489062892 cites W2068839843 @default.
• W1489062892 cites W2071062639 @default.
• W1489062892 cites W2075345253 @default.
• W1489062892 cites W2077135229 @default.
• W1489062892 cites W2077330278 @default.
• W1489062892 cites W2077743974 @default.
• W1489062892 cites W2078406556 @default.
• W1489062892 cites W2080497273 @default.
• W1489062892 cites W2084351275 @default.
• W1489062892 cites W2085140951 @default.
• W1489062892 cites W2090768993 @default.
• W1489062892 cites W2091782816 @default.
• W1489062892 cites W2092475403 @default.
• W1489062892 cites W2093096499 @default.
• W1489062892 cites W2094892689 @default.
• W1489062892 cites W2096876707 @default.
• W1489062892 cites W2096950785 @default.
• W1489062892 cites W2097378210 @default.
• W1489062892 cites W2097718079 @default.
• W1489062892 cites W2099480075 @default.
• W1489062892 cites W2099788034 @default.
• W1489062892 cites W2099939036 @default.
• W1489062892 cites W2101745239 @default.
• W1489062892 cites W2103920010 @default.
• W1489062892 cites W2107403336 @default.
• W1489062892 cites W2108453418 @default.
• W1489062892 cites W2113199099 @default.

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