Matches in SemOpenAlex for { <https://semopenalex.org/work/W1489086907> ?p ?o ?g. }
- W1489086907 endingPage "251" @default.
- W1489086907 startingPage "244" @default.
- W1489086907 abstract "For 3D-structure determination in biophysical systems EPR is rapidly gaining ground. Proteins labeled specifically with two nitroxide spin labels can be prepared, and several EPR methods are available for distance determination, which makes it possible to determine distance constraints. However, such methods require frozen solutions, potentially causing non-physiological states of the sample. Here, we target spin- spin interaction in liquid solution at room temperature using rigid model compounds. A series of 310 -helical peptides, based on α-aminoisobutyric acid (Aib), is synthesized with pairs of spin labels separated by three, four, and five amino acids. To avoid flexibility, the noncoded nitroxyl-containing α-amino acid TOAC that is rigidly connected with the peptide backbone, is used. The EPR spectra of the peptides show a decreasing amount of coupling between the two spin labels within this series. We suggest through-bond interaction as the dominating mechanism for exchange interaction (J) and find a stronger J-coupling than in the corresponding Ala-based TOAC-peptides investigated previously (Hanson, et al., J Am Chem Soc 1996, 118, 7618-7625). We speculate that stronger coupling in Aib- vs Ala- peptides is due to intrinsically stronger through-bond interaction in the Aib-based peptides." @default.
- W1489086907 created "2016-06-24" @default.
- W1489086907 creator A5036785927 @default.
- W1489086907 creator A5041758410 @default.
- W1489086907 creator A5046153410 @default.
- W1489086907 creator A5065741079 @default.
- W1489086907 creator A5078253107 @default.
- W1489086907 creator A5078323087 @default.
- W1489086907 date "2014-05-01" @default.
- W1489086907 modified "2023-10-04" @default.
- W1489086907 title "Conformation and EPR characterization of rigid, 3<sub>10</sub>-helical peptides with TOAC spin labels: Models for short distances" @default.
- W1489086907 cites W1964981541 @default.
- W1489086907 cites W1970587774 @default.
- W1489086907 cites W1981628805 @default.
- W1489086907 cites W1985240556 @default.
- W1489086907 cites W1988198291 @default.
- W1489086907 cites W1991673513 @default.
- W1489086907 cites W2001779113 @default.
- W1489086907 cites W2005471138 @default.
- W1489086907 cites W2017231526 @default.
- W1489086907 cites W2018105404 @default.
- W1489086907 cites W2020406711 @default.
- W1489086907 cites W2023290399 @default.
- W1489086907 cites W2024265636 @default.
- W1489086907 cites W2026232127 @default.
- W1489086907 cites W2031425316 @default.
- W1489086907 cites W2031989514 @default.
- W1489086907 cites W2033197694 @default.
- W1489086907 cites W2040113413 @default.
- W1489086907 cites W2040863970 @default.
- W1489086907 cites W2040926745 @default.
- W1489086907 cites W2048289988 @default.
- W1489086907 cites W2056126751 @default.
- W1489086907 cites W2058456588 @default.
- W1489086907 cites W2069246494 @default.
- W1489086907 cites W2071490247 @default.
- W1489086907 cites W2076713043 @default.
- W1489086907 cites W2079529074 @default.
- W1489086907 cites W2085416148 @default.
- W1489086907 cites W2085616004 @default.
- W1489086907 cites W2086610491 @default.
- W1489086907 cites W2091646550 @default.
- W1489086907 cites W2115320772 @default.
- W1489086907 cites W2125947653 @default.
- W1489086907 cites W2139754101 @default.
- W1489086907 cites W2146051607 @default.
- W1489086907 cites W2155585963 @default.
- W1489086907 cites W2316254521 @default.
- W1489086907 cites W2410534521 @default.
- W1489086907 cites W2488170673 @default.
- W1489086907 cites W2950571356 @default.
- W1489086907 cites W2952541549 @default.
- W1489086907 doi "https://doi.org/10.1002/bip.22467" @default.
- W1489086907 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24488683" @default.
- W1489086907 hasPublicationYear "2014" @default.
- W1489086907 type Work @default.
- W1489086907 sameAs 1489086907 @default.
- W1489086907 citedByCount "6" @default.
- W1489086907 countsByYear W14890869072015 @default.
- W1489086907 countsByYear W14890869072016 @default.
- W1489086907 countsByYear W14890869072017 @default.
- W1489086907 countsByYear W14890869072019 @default.
- W1489086907 countsByYear W14890869072023 @default.
- W1489086907 crossrefType "journal-article" @default.
- W1489086907 hasAuthorship W1489086907A5036785927 @default.
- W1489086907 hasAuthorship W1489086907A5041758410 @default.
- W1489086907 hasAuthorship W1489086907A5046153410 @default.
- W1489086907 hasAuthorship W1489086907A5065741079 @default.
- W1489086907 hasAuthorship W1489086907A5078253107 @default.
- W1489086907 hasAuthorship W1489086907A5078323087 @default.
- W1489086907 hasConcept C111998727 @default.
- W1489086907 hasConcept C121332964 @default.
- W1489086907 hasConcept C127413603 @default.
- W1489086907 hasConcept C131584629 @default.
- W1489086907 hasConcept C15920480 @default.
- W1489086907 hasConcept C169912494 @default.
- W1489086907 hasConcept C177462420 @default.
- W1489086907 hasConcept C178790620 @default.
- W1489086907 hasConcept C185592680 @default.
- W1489086907 hasConcept C187961010 @default.
- W1489086907 hasConcept C2776142628 @default.
- W1489086907 hasConcept C2779281246 @default.
- W1489086907 hasConcept C31684184 @default.
- W1489086907 hasConcept C42704618 @default.
- W1489086907 hasConcept C46141821 @default.
- W1489086907 hasConcept C515207424 @default.
- W1489086907 hasConcept C521977710 @default.
- W1489086907 hasConcept C55493867 @default.
- W1489086907 hasConcept C71240020 @default.
- W1489086907 hasConcept C78519656 @default.
- W1489086907 hasConcept C79123411 @default.
- W1489086907 hasConcept C8010536 @default.
- W1489086907 hasConcept C97355855 @default.
- W1489086907 hasConceptScore W1489086907C111998727 @default.
- W1489086907 hasConceptScore W1489086907C121332964 @default.
- W1489086907 hasConceptScore W1489086907C127413603 @default.
- W1489086907 hasConceptScore W1489086907C131584629 @default.
- W1489086907 hasConceptScore W1489086907C15920480 @default.