FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1489197112> ?p ?o ?g. }

• W1489197112 endingPage "20" @default.
• W1489197112 startingPage "13" @default.
• W1489197112 abstract "We describe the experience of the focal segmental glomerulosclerosis clinical trial (FSGS CT) in the identification and recruitment of participants into the study. This National Institutes of Health funded study, a multicenter, open-label, randomized comparison of cyclosporine versus oral dexamethasone pulses plus mycophenolate mofetil, experienced difficulty and delays meeting enrollment goals. These problems occurred despite the support of patient advocacy groups and aggressive recruitment strategies. Multiple barriers were identified including: (1) inaccurate estimates of the number of potential incident FSGS patients at participating centers; (2) delays in securing one of the test agents; (3) prolonged time between IRB approval and execution of a subcontract (mean 7.5 ± 0.8 months); (4) prolonged time between IRB approval and enrollment of the first patient at participating sites (mean 19.6 ± 1.4 months); and (5) reorganization of clinical coordinating core infrastructure to align resources with enrollment. A Web-based anonymous survey of site investigators revealed site-related barriers to patient recruitment. The value of a variety of recruitment tools was of marginal utility in facilitating patient enrollment. We conclude that improvements in the logistics of study approval and regulatory start-up and testing of promising novel agents are important factors in promoting enrollment into randomized clinical trials in nephrology. Clin Trans Sci 2013; Volume 6: 13–20" @default.
• W1489197112 created "2016-06-24" @default.
• W1489197112 creator A5005930986 @default.
• W1489197112 creator A5014167400 @default.
• W1489197112 creator A5014996075 @default.
• W1489197112 creator A5015027317 @default.
• W1489197112 creator A5015327454 @default.
• W1489197112 creator A5017944258 @default.
• W1489197112 creator A5020271560 @default.
• W1489197112 creator A5026543622 @default.
• W1489197112 creator A5029482359 @default.
• W1489197112 creator A5035165984 @default.
• W1489197112 creator A5036398129 @default.
• W1489197112 creator A5048128579 @default.
• W1489197112 creator A5049127856 @default.
• W1489197112 creator A5054993212 @default.
• W1489197112 creator A5060923071 @default.
• W1489197112 creator A5064770359 @default.
• W1489197112 creator A5068647039 @default.
• W1489197112 creator A5072312928 @default.
• W1489197112 date "2012-10-30" @default.
• W1489197112 modified "2023-09-27" @default.
• W1489197112 title "Patient Recruitment into a Multicenter Randomized Clinical Trial for Kidney Disease: Report of the Focal Segmental Glomerulosclerosis Clinical Trial (FSGS CT)" @default.
• W1489197112 cites W1967985363 @default.
• W1489197112 cites W1969287567 @default.
• W1489197112 cites W1972855150 @default.
• W1489197112 cites W1977991117 @default.
• W1489197112 cites W2006598011 @default.
• W1489197112 cites W2029027295 @default.
• W1489197112 cites W2041888064 @default.
• W1489197112 cites W2055721015 @default.
• W1489197112 cites W2057225146 @default.
• W1489197112 cites W2061330000 @default.
• W1489197112 cites W2069124079 @default.
• W1489197112 cites W2079391262 @default.
• W1489197112 cites W2082770695 @default.
• W1489197112 cites W2087571465 @default.
• W1489197112 cites W2092565635 @default.
• W1489197112 cites W2124898212 @default.
• W1489197112 cites W2136424505 @default.
• W1489197112 cites W2148195379 @default.
• W1489197112 cites W2155047659 @default.
• W1489197112 cites W2167583143 @default.
• W1489197112 cites W2171617131 @default.
• W1489197112 doi "https://doi.org/10.1111/cts.12003" @default.
• W1489197112 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4698888" @default.
• W1489197112 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23399084" @default.
• W1489197112 hasPublicationYear "2012" @default.
• W1489197112 type Work @default.
• W1489197112 sameAs 1489197112 @default.
• W1489197112 citedByCount "14" @default.
• W1489197112 countsByYear W14891971122013 @default.
• W1489197112 countsByYear W14891971122014 @default.
• W1489197112 countsByYear W14891971122015 @default.
• W1489197112 countsByYear W14891971122016 @default.
• W1489197112 countsByYear W14891971122017 @default.
• W1489197112 countsByYear W14891971122019 @default.
• W1489197112 countsByYear W14891971122021 @default.
• W1489197112 countsByYear W14891971122022 @default.
• W1489197112 countsByYear W14891971122023 @default.
• W1489197112 crossrefType "journal-article" @default.
• W1489197112 hasAuthorship W1489197112A5005930986 @default.
• W1489197112 hasAuthorship W1489197112A5014167400 @default.
• W1489197112 hasAuthorship W1489197112A5014996075 @default.
• W1489197112 hasAuthorship W1489197112A5015027317 @default.
• W1489197112 hasAuthorship W1489197112A5015327454 @default.
• W1489197112 hasAuthorship W1489197112A5017944258 @default.
• W1489197112 hasAuthorship W1489197112A5020271560 @default.
• W1489197112 hasAuthorship W1489197112A5026543622 @default.
• W1489197112 hasAuthorship W1489197112A5029482359 @default.
• W1489197112 hasAuthorship W1489197112A5035165984 @default.
• W1489197112 hasAuthorship W1489197112A5036398129 @default.
• W1489197112 hasAuthorship W1489197112A5048128579 @default.
• W1489197112 hasAuthorship W1489197112A5049127856 @default.
• W1489197112 hasAuthorship W1489197112A5054993212 @default.
• W1489197112 hasAuthorship W1489197112A5060923071 @default.
• W1489197112 hasAuthorship W1489197112A5064770359 @default.
• W1489197112 hasAuthorship W1489197112A5068647039 @default.
• W1489197112 hasAuthorship W1489197112A5072312928 @default.
• W1489197112 hasBestOaLocation W14891971122 @default.
• W1489197112 hasConcept C126322002 @default.
• W1489197112 hasConcept C168563851 @default.
• W1489197112 hasConcept C177713679 @default.
• W1489197112 hasConcept C2777747828 @default.
• W1489197112 hasConcept C2778415529 @default.
• W1489197112 hasConcept C2779174308 @default.
• W1489197112 hasConcept C2779561371 @default.
• W1489197112 hasConcept C2780091579 @default.
• W1489197112 hasConcept C535046627 @default.
• W1489197112 hasConcept C54847362 @default.
• W1489197112 hasConcept C71924100 @default.
• W1489197112 hasConceptScore W1489197112C126322002 @default.
• W1489197112 hasConceptScore W1489197112C168563851 @default.
• W1489197112 hasConceptScore W1489197112C177713679 @default.
• W1489197112 hasConceptScore W1489197112C2777747828 @default.
• W1489197112 hasConceptScore W1489197112C2778415529 @default.
• W1489197112 hasConceptScore W1489197112C2779174308 @default.
• W1489197112 hasConceptScore W1489197112C2779561371 @default.

• next