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- W1489231383 abstract "Recent advances in mass spectrometry have led to a paradigm shift in bioanalytical support within drug metabolism and pharmacokinetics groups. Quantitation and qualitative metabolite identification (quant-qual) is beginning to merge into one experiment. The expectations of very short data turnaround times of drug discovery scientists are in part driving this change. Bioanalytical scientists are expected to increase both the speed and the efficiency of their experiments providing feedback on not only the rate of metabolism but also the sites of metabolic lability within a few days. The goals of this chapter are to describe the developments in mass spectrometry that have led to these changes and to give illustrative examples of how this technology is being used for drug discovery support." @default.
- W1489231383 created "2016-06-24" @default.
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- W1489231383 date "2013-08-30" @default.
- W1489231383 modified "2023-10-14" @default.
- W1489231383 title "Simultaneous LC‐MS Quantitation and Metabolite Identification in Drug Metabolism and Pharmacokinetics" @default.
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- W1489231383 doi "https://doi.org/10.1002/9781118671276.ch33" @default.
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