FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1489320608> ?p ?o ?g. }

• W1489320608 abstract "The ability of mesenchymal stem cells (MSCs) to differentiate into many cell types, and modulate immune responses, makes them an attractive therapeutic tool for cell transplantation and tissue engineering.This project was designed for isolation, culture, and characterization of human marrow-derived MSCs based on the immunophenotypic markers and the differentiation potential.Bone marrow of healthy donors was aspirated from the iliac crest. Mononuclear cells were layered over the Ficoll-Paque density-gradient and plated in tissue cultures dish. The adherent cells expanded rapidly and maintained with periodic passages until a relatively homogeneous population was established. The identification of adherent cells and the immune-surface markers was performed by flow cytometric analysis at the third passage. The in vitro differentiation of MSCs into osteoblast and adipocytes was also achieved.The MSCs were CD11b (CR3), CD45, CD34, CD31 (PCAM-1), CD40, CD80 (B7-1), and HLA-class II negative because antigen expression was less than 5%, while they showed a high expression of CD90, and CD73. The differentiation of osteoblasts, is determined by deposition of a mineralized extracellular matrix in the culture plates that can be detected with Alizarin Red. Adipocytes were easily identified by their morphology and staining with Oil Red.MSCs can be isolated and expanded from most healthy donors, providing for a source of cell-based therapy." @default.
• W1489320608 created "2016-06-24" @default.
• W1489320608 creator A5004096793 @default.
• W1489320608 creator A5019933856 @default.
• W1489320608 creator A5029559226 @default.
• W1489320608 creator A5038476250 @default.
• W1489320608 creator A5044807152 @default.
• W1489320608 creator A5057820166 @default.
• W1489320608 creator A5069657291 @default.
• W1489320608 creator A5084556010 @default.
• W1489320608 creator A5084802759 @default.
• W1489320608 creator A5091618884 @default.
• W1489320608 date "2012-01-01" @default.
• W1489320608 modified "2023-10-10" @default.
• W1489320608 title "Human Bone Marrow-derived Mesenchymal Stem Cell: A Source for Cell-Based Therapy." @default.
• W1489320608 cites W1493043296 @default.
• W1489320608 cites W1965425745 @default.
• W1489320608 cites W1998246678 @default.
• W1489320608 cites W2016931709 @default.
• W1489320608 cites W2025803508 @default.
• W1489320608 cites W2038467210 @default.
• W1489320608 cites W2054274983 @default.
• W1489320608 cites W2060341044 @default.
• W1489320608 cites W2069006548 @default.
• W1489320608 cites W2098459519 @default.
• W1489320608 cites W2107989515 @default.
• W1489320608 cites W2128406549 @default.
• W1489320608 cites W2131004666 @default.
• W1489320608 cites W2134044855 @default.
• W1489320608 cites W2147003363 @default.
• W1489320608 cites W2162699339 @default.
• W1489320608 cites W2168800437 @default.
• W1489320608 cites W3142363567 @default.
• W1489320608 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4089277" @default.
• W1489320608 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25013621" @default.
• W1489320608 hasPublicationYear "2012" @default.
• W1489320608 type Work @default.
• W1489320608 sameAs 1489320608 @default.
• W1489320608 citedByCount "11" @default.
• W1489320608 countsByYear W14893206082014 @default.
• W1489320608 countsByYear W14893206082017 @default.
• W1489320608 countsByYear W14893206082018 @default.
• W1489320608 countsByYear W14893206082020 @default.
• W1489320608 countsByYear W14893206082023 @default.
• W1489320608 crossrefType "journal-article" @default.
• W1489320608 hasAuthorship W1489320608A5004096793 @default.
• W1489320608 hasAuthorship W1489320608A5019933856 @default.
• W1489320608 hasAuthorship W1489320608A5029559226 @default.
• W1489320608 hasAuthorship W1489320608A5038476250 @default.
• W1489320608 hasAuthorship W1489320608A5044807152 @default.
• W1489320608 hasAuthorship W1489320608A5057820166 @default.
• W1489320608 hasAuthorship W1489320608A5069657291 @default.
• W1489320608 hasAuthorship W1489320608A5084556010 @default.
• W1489320608 hasAuthorship W1489320608A5084802759 @default.
• W1489320608 hasAuthorship W1489320608A5091618884 @default.
• W1489320608 hasConcept C10205521 @default.
• W1489320608 hasConcept C10882517 @default.
• W1489320608 hasConcept C116716535 @default.
• W1489320608 hasConcept C142724271 @default.
• W1489320608 hasConcept C198826908 @default.
• W1489320608 hasConcept C202751555 @default.
• W1489320608 hasConcept C203014093 @default.
• W1489320608 hasConcept C204232928 @default.
• W1489320608 hasConcept C2778260815 @default.
• W1489320608 hasConcept C2778939058 @default.
• W1489320608 hasConcept C2780007613 @default.
• W1489320608 hasConcept C28328180 @default.
• W1489320608 hasConcept C55493867 @default.
• W1489320608 hasConcept C71924100 @default.
• W1489320608 hasConcept C86803240 @default.
• W1489320608 hasConcept C95444343 @default.
• W1489320608 hasConceptScore W1489320608C10205521 @default.
• W1489320608 hasConceptScore W1489320608C10882517 @default.
• W1489320608 hasConceptScore W1489320608C116716535 @default.
• W1489320608 hasConceptScore W1489320608C142724271 @default.
• W1489320608 hasConceptScore W1489320608C198826908 @default.
• W1489320608 hasConceptScore W1489320608C202751555 @default.
• W1489320608 hasConceptScore W1489320608C203014093 @default.
• W1489320608 hasConceptScore W1489320608C204232928 @default.
• W1489320608 hasConceptScore W1489320608C2778260815 @default.
• W1489320608 hasConceptScore W1489320608C2778939058 @default.
• W1489320608 hasConceptScore W1489320608C2780007613 @default.
• W1489320608 hasConceptScore W1489320608C28328180 @default.
• W1489320608 hasConceptScore W1489320608C55493867 @default.
• W1489320608 hasConceptScore W1489320608C71924100 @default.
• W1489320608 hasConceptScore W1489320608C86803240 @default.
• W1489320608 hasConceptScore W1489320608C95444343 @default.
• W1489320608 hasLocation W14893206081 @default.
• W1489320608 hasOpenAccess W1489320608 @default.
• W1489320608 hasPrimaryLocation W14893206081 @default.
• W1489320608 hasRelatedWork W1845462896 @default.
• W1489320608 hasRelatedWork W1942897874 @default.
• W1489320608 hasRelatedWork W1945446420 @default.
• W1489320608 hasRelatedWork W1967764991 @default.
• W1489320608 hasRelatedWork W2000330544 @default.
• W1489320608 hasRelatedWork W2035582618 @default.
• W1489320608 hasRelatedWork W2184403216 @default.
• W1489320608 hasRelatedWork W2349544807 @default.
• W1489320608 hasRelatedWork W2363847073 @default.
• W1489320608 hasRelatedWork W2369501697 @default.

• next