Matches in SemOpenAlex for { <https://semopenalex.org/work/W1489361657> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W1489361657 abstract "Abstract : This final report summarizes our work on the effectiveness of a new adenovirus based optical imaging vector designed to detect MAP kinase levels in living subjects. The vector was injected into human tumors implanted into SCID mice. Animals were injected with D-luciferin and imaged in a Xenogen IVIS device. The vector was able to detect enhanced MAPK levels stimulated by Epidermal Growth Factor in prostate cancer tumors of xenograft animals. We interrogated two lines of androgen dependent (AD) and independent (Al) xenograft animal models (CWR22 and LAPC9) to determine MAPK levels. We found no significant difference between AD and Al cancer with respect to functional MAPK levels. However, CWR22 animals exhibit significantly higher MAPK levels than LAPC9 xenograft animals. The data suggest the possibility that gene expression based imaging may be able to detect augmented MAPK levels predictive of disease progression as well as the efficacy of cancer therapeutics." @default.
- W1489361657 created "2016-06-24" @default.
- W1489361657 creator A5040925674 @default.
- W1489361657 date "2003-10-01" @default.
- W1489361657 modified "2023-09-24" @default.
- W1489361657 title "Interrogating Androgen Receptor Mediated Gene Expression and Tumor Progression by Molecular Imaging" @default.
- W1489361657 cites W1580523172 @default.
- W1489361657 cites W1948931726 @default.
- W1489361657 cites W1965674043 @default.
- W1489361657 cites W1969241521 @default.
- W1489361657 cites W1979647722 @default.
- W1489361657 cites W1980046172 @default.
- W1489361657 cites W1985596446 @default.
- W1489361657 cites W1985827132 @default.
- W1489361657 cites W1991995900 @default.
- W1489361657 cites W1995115168 @default.
- W1489361657 cites W2000082154 @default.
- W1489361657 cites W2002718660 @default.
- W1489361657 cites W2003955264 @default.
- W1489361657 cites W2007662459 @default.
- W1489361657 cites W2016543883 @default.
- W1489361657 cites W2022635468 @default.
- W1489361657 cites W2041098455 @default.
- W1489361657 cites W2041266730 @default.
- W1489361657 cites W2046234516 @default.
- W1489361657 cites W2063119860 @default.
- W1489361657 cites W2064282853 @default.
- W1489361657 cites W2064293531 @default.
- W1489361657 cites W2074497307 @default.
- W1489361657 cites W2076011256 @default.
- W1489361657 cites W2077863736 @default.
- W1489361657 cites W2087668717 @default.
- W1489361657 cites W2095156669 @default.
- W1489361657 cites W2095416319 @default.
- W1489361657 cites W2109490785 @default.
- W1489361657 cites W2109589384 @default.
- W1489361657 cites W2117272440 @default.
- W1489361657 cites W2119507443 @default.
- W1489361657 cites W2124245112 @default.
- W1489361657 cites W2125069527 @default.
- W1489361657 cites W2126496338 @default.
- W1489361657 cites W2129925175 @default.
- W1489361657 cites W2132190684 @default.
- W1489361657 cites W2134043419 @default.
- W1489361657 cites W2140855177 @default.
- W1489361657 cites W2146104410 @default.
- W1489361657 cites W2146352944 @default.
- W1489361657 cites W2147117661 @default.
- W1489361657 cites W2151226921 @default.
- W1489361657 cites W2153030011 @default.
- W1489361657 cites W2157330336 @default.
- W1489361657 cites W2158200577 @default.
- W1489361657 cites W2158235081 @default.
- W1489361657 cites W2159448513 @default.
- W1489361657 cites W2160084272 @default.
- W1489361657 cites W2160564412 @default.
- W1489361657 cites W2334671443 @default.
- W1489361657 doi "https://doi.org/10.21236/ada419790" @default.
- W1489361657 hasPublicationYear "2003" @default.
- W1489361657 type Work @default.
- W1489361657 sameAs 1489361657 @default.
- W1489361657 citedByCount "0" @default.
- W1489361657 crossrefType "report" @default.
- W1489361657 hasAuthorship W1489361657A5040925674 @default.
- W1489361657 hasConcept C104317684 @default.
- W1489361657 hasConcept C121608353 @default.
- W1489361657 hasConcept C150194340 @default.
- W1489361657 hasConcept C2780192828 @default.
- W1489361657 hasConcept C502942594 @default.
- W1489361657 hasConcept C54355233 @default.
- W1489361657 hasConcept C61367390 @default.
- W1489361657 hasConcept C86803240 @default.
- W1489361657 hasConceptScore W1489361657C104317684 @default.
- W1489361657 hasConceptScore W1489361657C121608353 @default.
- W1489361657 hasConceptScore W1489361657C150194340 @default.
- W1489361657 hasConceptScore W1489361657C2780192828 @default.
- W1489361657 hasConceptScore W1489361657C502942594 @default.
- W1489361657 hasConceptScore W1489361657C54355233 @default.
- W1489361657 hasConceptScore W1489361657C61367390 @default.
- W1489361657 hasConceptScore W1489361657C86803240 @default.
- W1489361657 hasLocation W14893616571 @default.
- W1489361657 hasOpenAccess W1489361657 @default.
- W1489361657 hasPrimaryLocation W14893616571 @default.
- W1489361657 hasRelatedWork W1969676666 @default.
- W1489361657 hasRelatedWork W2005360200 @default.
- W1489361657 hasRelatedWork W2009966535 @default.
- W1489361657 hasRelatedWork W2019988726 @default.
- W1489361657 hasRelatedWork W2051461989 @default.
- W1489361657 hasRelatedWork W2088063203 @default.
- W1489361657 hasRelatedWork W2097265502 @default.
- W1489361657 hasRelatedWork W2171277769 @default.
- W1489361657 hasRelatedWork W2423871774 @default.
- W1489361657 hasRelatedWork W3033910563 @default.
- W1489361657 isParatext "false" @default.
- W1489361657 isRetracted "false" @default.
- W1489361657 magId "1489361657" @default.
- W1489361657 workType "report" @default.