FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1489385604> ?p ?o ?g. }

• W1489385604 endingPage "248" @default.
• W1489385604 startingPage "243" @default.
• W1489385604 abstract "The production of enterotoxin A and nuclease by Staphylococcus aureus strain 100 was studied in a 1.0-liter fermentor. The effects of the gas flow rate, pH, and dissolved oxygen were evaluated. Toxin and nuclease secretion occurred under all conditions which permitted growth of the organism. Final yields of toxin and nuclease in cultures grown at constant air flow rates, ranging from 50 to 500 cm3 per min, were higher at successively higher flow rates. An optimum flow rate for either toxin or nuclease production was not observed. When the aeration rate alone or aeration rate and pH were held constant, the dissolved oxygen levels in the culture decreased from the initial 100% level to 0 to 5% 3 to 4 h after inoculation. The O2 demand of the culture then maintained this level for an additional 4 to 5 h. This low dissolved oxygen interval was characterized by rapid growth and extracellular protein production. Controlling the dissolved oxygen at a constant level throughout growth did not increase the final levels of toxin and nuclease above those achieved at the respective constant pH values. Growth under the influence of a constant aeration rate of 500 cm3 per min and a constant pH of 6.5 and 7.0 yielded the highest titers of nuclease (1,550 units/ml) and toxin (10.5 mug/ml) obtained in any of the fermentations conducted in this study. Sparging fermentor cultures with pure oxygen at a rate of 100 cm3 per min yielded growth and extracellular protein levels similar to those achieved at the sparge rate of 500 cm3 of air per min. Controlling the dissolved oxygen at 100% of pure oxygen saturation appeared to inhibit the culture, as the final cultural turbidity as well as the levels of toxin and nuclease were reduced. These data indicate that enterotoxin and nuclease secretions are closely associated with the growth of strain 100. Analyses of the production rates of these components indicated that early log phase was the most efficient production interval in the growth cycle and that this efficiency was increased by pH control at 6.7 to 6.8 and dissolved oxygen control at 10% of air saturation." @default.
• W1489385604 created "2016-06-24" @default.
• W1489385604 creator A5043086459 @default.
• W1489385604 creator A5061230496 @default.
• W1489385604 date "1976-02-01" @default.
• W1489385604 modified "2023-09-25" @default.
• W1489385604 title "Synthesis of staphylococcal enterotoxin A and nuclease under controlled fermentor conditions" @default.
• W1489385604 cites W1519005032 @default.
• W1489385604 cites W1571351095 @default.
• W1489385604 cites W1581226884 @default.
• W1489385604 cites W1827924542 @default.
• W1489385604 cites W1866034678 @default.
• W1489385604 cites W1937159632 @default.
• W1489385604 cites W2108590287 @default.
• W1489385604 cites W2164054436 @default.
• W1489385604 cites W76708712 @default.
• W1489385604 doi "https://doi.org/10.1128/aem.31.2.243-248.1976" @default.
• W1489385604 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/169754" @default.
• W1489385604 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11744" @default.
• W1489385604 hasPublicationYear "1976" @default.
• W1489385604 type Work @default.
• W1489385604 sameAs 1489385604 @default.
• W1489385604 citedByCount "21" @default.
• W1489385604 countsByYear W14893856042014 @default.
• W1489385604 countsByYear W14893856042016 @default.
• W1489385604 countsByYear W14893856042018 @default.
• W1489385604 crossrefType "journal-article" @default.
• W1489385604 hasAuthorship W1489385604A5043086459 @default.
• W1489385604 hasAuthorship W1489385604A5061230496 @default.
• W1489385604 hasBestOaLocation W14893856041 @default.
• W1489385604 hasConcept C100544194 @default.
• W1489385604 hasConcept C104317684 @default.
• W1489385604 hasConcept C178790620 @default.
• W1489385604 hasConcept C181199279 @default.
• W1489385604 hasConcept C185592680 @default.
• W1489385604 hasConcept C2777271071 @default.
• W1489385604 hasConcept C2777367657 @default.
• W1489385604 hasConcept C31903555 @default.
• W1489385604 hasConcept C43617362 @default.
• W1489385604 hasConcept C540031477 @default.
• W1489385604 hasConcept C547475151 @default.
• W1489385604 hasConcept C55493867 @default.
• W1489385604 hasConcept C66999527 @default.
• W1489385604 hasConcept C86803240 @default.
• W1489385604 hasConcept C86922832 @default.
• W1489385604 hasConcept C89423630 @default.
• W1489385604 hasConceptScore W1489385604C100544194 @default.
• W1489385604 hasConceptScore W1489385604C104317684 @default.
• W1489385604 hasConceptScore W1489385604C178790620 @default.
• W1489385604 hasConceptScore W1489385604C181199279 @default.
• W1489385604 hasConceptScore W1489385604C185592680 @default.
• W1489385604 hasConceptScore W1489385604C2777271071 @default.
• W1489385604 hasConceptScore W1489385604C2777367657 @default.
• W1489385604 hasConceptScore W1489385604C31903555 @default.
• W1489385604 hasConceptScore W1489385604C43617362 @default.
• W1489385604 hasConceptScore W1489385604C540031477 @default.
• W1489385604 hasConceptScore W1489385604C547475151 @default.
• W1489385604 hasConceptScore W1489385604C55493867 @default.
• W1489385604 hasConceptScore W1489385604C66999527 @default.
• W1489385604 hasConceptScore W1489385604C86803240 @default.
• W1489385604 hasConceptScore W1489385604C86922832 @default.
• W1489385604 hasConceptScore W1489385604C89423630 @default.
• W1489385604 hasIssue "2" @default.
• W1489385604 hasLocation W14893856041 @default.
• W1489385604 hasOpenAccess W1489385604 @default.
• W1489385604 hasPrimaryLocation W14893856041 @default.
• W1489385604 hasRelatedWork W1526415124 @default.
• W1489385604 hasRelatedWork W1552051572 @default.
• W1489385604 hasRelatedWork W1561128429 @default.
• W1489385604 hasRelatedWork W1591103101 @default.
• W1489385604 hasRelatedWork W1914569136 @default.
• W1489385604 hasRelatedWork W2001360571 @default.
• W1489385604 hasRelatedWork W2081759813 @default.
• W1489385604 hasRelatedWork W2415173381 @default.
• W1489385604 hasRelatedWork W988217133 @default.
• W1489385604 hasRelatedWork W72454204 @default.
• W1489385604 hasVolume "31" @default.
• W1489385604 isParatext "false" @default.
• W1489385604 isRetracted "false" @default.
• W1489385604 magId "1489385604" @default.
• W1489385604 workType "article" @default.