Matches in SemOpenAlex for { <https://semopenalex.org/work/W1489425699> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W1489425699 endingPage "1268" @default.
- W1489425699 startingPage "1262" @default.
- W1489425699 abstract "Article history Diabetes mellitus is the commonest endocrine disorder that affects more than 360 million people worldwide. Use of herbal antidiabetic formulations along with allopathic antidiabetic medicines is increasing in order to achieve efficient treatment. Concurrent administration of herb and drug can lead to pharmacodynamic and pharmacokinetic interactions changing the efficacy. In present study probable interaction between gymnema tea (herbal antidiabetic formulation) and metformin is determined. Interaction study was based on comparison of antidiabetic activity of metformin in presence and absence of gymnema tea in diabetes induced albino rats. For the interaction studies albino rats were divided into four groups. Group I (Normal), Group II (Diabetes induced Control), Group III (Diabetes induced animals treated with metformin alone) and Group IV (Diabetes induced animals treated with combination of metformin and Gymnema Tea). Animals received metformin treatment (50 mg/kg) for a period of 28 days after induction of diabetes. At an interval of 0 min, 30 min, 1 hr, 2 hrs, 4 hrs, 8 hrs, 12 hrs, 24 hrs, 7 th day, 14 th day, 21 st day and 28 th day of drug treatment blood was withdrawn from retro orbital sinus. Metformin was extracted from plasma following liquid - liquid extraction and the plasma concentration of metformin by HPLC and blood glucose level was determined. At different time intervals there was decrease in plasma metformin concentrations and increase in blood glucose levels of group IV rats compared to group III rats indicating a potential drug - herb interaction between metformin and gymnema tea." @default.
- W1489425699 created "2016-06-24" @default.
- W1489425699 creator A5018064188 @default.
- W1489425699 creator A5040532747 @default.
- W1489425699 creator A5048107324 @default.
- W1489425699 creator A5048629027 @default.
- W1489425699 creator A5083579256 @default.
- W1489425699 date "2013-01-01" @default.
- W1489425699 modified "2023-09-27" @default.
- W1489425699 title "EVALUATION OF INFLUENCE OF GYMNEMA TEA ON ANTIDIABETIC ACTIVITY OF METFORMIN IN DIABETIC RATS" @default.
- W1489425699 cites W154741123 @default.
- W1489425699 cites W1970097416 @default.
- W1489425699 cites W1971630753 @default.
- W1489425699 cites W1979951535 @default.
- W1489425699 cites W1999328035 @default.
- W1489425699 cites W2000999406 @default.
- W1489425699 cites W2021826135 @default.
- W1489425699 cites W2045308912 @default.
- W1489425699 cites W2065202941 @default.
- W1489425699 cites W2120156554 @default.
- W1489425699 cites W2125525623 @default.
- W1489425699 hasPublicationYear "2013" @default.
- W1489425699 type Work @default.
- W1489425699 sameAs 1489425699 @default.
- W1489425699 citedByCount "0" @default.
- W1489425699 crossrefType "journal-article" @default.
- W1489425699 hasAuthorship W1489425699A5018064188 @default.
- W1489425699 hasAuthorship W1489425699A5040532747 @default.
- W1489425699 hasAuthorship W1489425699A5048107324 @default.
- W1489425699 hasAuthorship W1489425699A5048629027 @default.
- W1489425699 hasAuthorship W1489425699A5083579256 @default.
- W1489425699 hasConcept C111113717 @default.
- W1489425699 hasConcept C112705442 @default.
- W1489425699 hasConcept C126322002 @default.
- W1489425699 hasConcept C134018914 @default.
- W1489425699 hasConcept C162156334 @default.
- W1489425699 hasConcept C2780323712 @default.
- W1489425699 hasConcept C555293320 @default.
- W1489425699 hasConcept C556039675 @default.
- W1489425699 hasConcept C71924100 @default.
- W1489425699 hasConcept C98274493 @default.
- W1489425699 hasConceptScore W1489425699C111113717 @default.
- W1489425699 hasConceptScore W1489425699C112705442 @default.
- W1489425699 hasConceptScore W1489425699C126322002 @default.
- W1489425699 hasConceptScore W1489425699C134018914 @default.
- W1489425699 hasConceptScore W1489425699C162156334 @default.
- W1489425699 hasConceptScore W1489425699C2780323712 @default.
- W1489425699 hasConceptScore W1489425699C555293320 @default.
- W1489425699 hasConceptScore W1489425699C556039675 @default.
- W1489425699 hasConceptScore W1489425699C71924100 @default.
- W1489425699 hasConceptScore W1489425699C98274493 @default.
- W1489425699 hasIssue "12" @default.
- W1489425699 hasLocation W14894256991 @default.
- W1489425699 hasOpenAccess W1489425699 @default.
- W1489425699 hasPrimaryLocation W14894256991 @default.
- W1489425699 hasRelatedWork W1969211084 @default.
- W1489425699 hasRelatedWork W2076489478 @default.
- W1489425699 hasRelatedWork W2079984349 @default.
- W1489425699 hasRelatedWork W2110837677 @default.
- W1489425699 hasRelatedWork W2137007924 @default.
- W1489425699 hasRelatedWork W2184542443 @default.
- W1489425699 hasRelatedWork W2187571769 @default.
- W1489425699 hasRelatedWork W2253915337 @default.
- W1489425699 hasRelatedWork W2284923424 @default.
- W1489425699 hasRelatedWork W2338469652 @default.
- W1489425699 hasRelatedWork W2417638637 @default.
- W1489425699 hasRelatedWork W2514554162 @default.
- W1489425699 hasRelatedWork W2554666118 @default.
- W1489425699 hasRelatedWork W2588274867 @default.
- W1489425699 hasRelatedWork W2767779979 @default.
- W1489425699 hasRelatedWork W3133325749 @default.
- W1489425699 hasRelatedWork W3152937173 @default.
- W1489425699 hasRelatedWork W3157656442 @default.
- W1489425699 hasRelatedWork W1493114349 @default.
- W1489425699 hasRelatedWork W1608675935 @default.
- W1489425699 hasVolume "3" @default.
- W1489425699 isParatext "false" @default.
- W1489425699 isRetracted "false" @default.
- W1489425699 magId "1489425699" @default.
- W1489425699 workType "article" @default.