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• W1489496527 endingPage "309" @default.
• W1489496527 startingPage "298" @default.
• W1489496527 abstract "Lipid droplets are ubiquitous cellular structures involved in energy homeostasis and metabolism that have long been considered as simple inert deposits of lipid. Here, we show that lipid droplets are bona fide organelles that are actively partitioned between mother cell and daughter cell in Saccharomyces cerevisiae. Video microscopy revealed that a subset of lipid droplets moves from mother cell to bud in an ordered, vectorial process, while the remaining lipid droplets are retained by the mother cell. Bud-directed movement of lipid droplets is mediated by the molecular motor Myo2p, while retention of lipid droplets occurs at the perinuclear endoplasmic reticulum. Lipid droplets are thus apportioned between mother cell and daughter cell at cell division rather than being made anew." @default.
• W1489496527 created "2016-06-24" @default.
• W1489496527 creator A5035253921 @default.
• W1489496527 creator A5047263915 @default.
• W1489496527 date "2015-01-06" @default.
• W1489496527 modified "2023-10-12" @default.
• W1489496527 title "Transport and Retention Mechanisms Govern Lipid Droplet Inheritance in<i>Saccharomyces cerevisiae</i>" @default.
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• W1489496527 doi "https://doi.org/10.1111/tra.12247" @default.
• W1489496527 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25524182" @default.
• W1489496527 hasPublicationYear "2015" @default.
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