FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1489652016> ?p ?o ?g. }

• W1489652016 endingPage "8" @default.
• W1489652016 startingPage "1" @default.
• W1489652016 abstract "The purpose of this study was to investigate the serum proteins biomarkers by label-free liquid chromatography coupled to tandem mass spectrometry quantification methods in the Chinese patients with acute ischemic stroke (AIS).In the study period, sera from 40 AIS patients and 40 normal cases were selected for screening study. The selected protein associations with disease risk were further evaluated by enzyme-linked immunosorbent assay (ELISA) testing of the remaining stroke cases and controls. Its value for biomarkers diagnosis was appreciated through receiver operating characteristic (ROC) curve.Patients versus control levels differences were suggested for 19 proteins (nominal P < 0.05) for stroke, with three proteins having a false discovery rate <0.05. The association of mannose-binding lectin (MBL) with stroke (P < 0.001) was confirmed using ELISA in replication studies. Based on the ROC curve, the optimal serum concentration of MBL as a surrogate marker to support the diagnosis of ischemic cerebral injury was found to be 1050 ug/L, which yielded a sensitivity of 81.8% and a specificity of 80.2%, the area under the curve was 0.812 (95% CI: 0.724-0.876). In multivariate analysis, there was an increased risk of AIS associated with MBL levels ≥1050 ug/L (OR: 4.76, 95% CI: 1.59-10.12) after adjusting for possible confounders.The discovery and replication studies presented here show MBL to be a risk marker for AIS in the Chinese population, which appears to be a novel finding." @default.
• W1489652016 created "2016-06-24" @default.
• W1489652016 creator A5000442440 @default.
• W1489652016 creator A5015612759 @default.
• W1489652016 creator A5027714717 @default.
• W1489652016 creator A5052917711 @default.
• W1489652016 date "2015-05-22" @default.
• W1489652016 modified "2023-09-27" @default.
• W1489652016 title "Serum protein biomarkers screening in patients with ischemic stroke by LC-MS/MS" @default.
• W1489652016 cites W1588757304 @default.
• W1489652016 cites W1677439338 @default.
• W1489652016 cites W1972020024 @default.
• W1489652016 cites W1980034029 @default.
• W1489652016 cites W1983148583 @default.
• W1489652016 cites W1986887325 @default.
• W1489652016 cites W1993354346 @default.
• W1489652016 cites W1998211475 @default.
• W1489652016 cites W2001344264 @default.
• W1489652016 cites W2002815598 @default.
• W1489652016 cites W2007414618 @default.
• W1489652016 cites W2011846108 @default.
• W1489652016 cites W2013771003 @default.
• W1489652016 cites W2014032285 @default.
• W1489652016 cites W2014803646 @default.
• W1489652016 cites W2015671694 @default.
• W1489652016 cites W2024288744 @default.
• W1489652016 cites W2028048426 @default.
• W1489652016 cites W2047979760 @default.
• W1489652016 cites W2050963407 @default.
• W1489652016 cites W2051526721 @default.
• W1489652016 cites W2054218003 @default.
• W1489652016 cites W2057740457 @default.
• W1489652016 cites W2065250447 @default.
• W1489652016 cites W2071450653 @default.
• W1489652016 cites W2078103827 @default.
• W1489652016 cites W2080504768 @default.
• W1489652016 cites W2098142641 @default.
• W1489652016 cites W2105614022 @default.
• W1489652016 cites W2113288814 @default.
• W1489652016 cites W2137501231 @default.
• W1489652016 cites W2138595885 @default.
• W1489652016 cites W2146205259 @default.
• W1489652016 cites W2156250197 @default.
• W1489652016 cites W2162128341 @default.
• W1489652016 cites W2167443016 @default.
• W1489652016 cites W2170872186 @default.
• W1489652016 doi "https://doi.org/10.3109/00207454.2015.1033713" @default.
• W1489652016 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26000912" @default.
• W1489652016 hasPublicationYear "2015" @default.
• W1489652016 type Work @default.
• W1489652016 sameAs 1489652016 @default.
• W1489652016 citedByCount "0" @default.
• W1489652016 crossrefType "journal-article" @default.
• W1489652016 hasAuthorship W1489652016A5000442440 @default.
• W1489652016 hasAuthorship W1489652016A5015612759 @default.
• W1489652016 hasAuthorship W1489652016A5027714717 @default.
• W1489652016 hasAuthorship W1489652016A5052917711 @default.
• W1489652016 hasConcept C126322002 @default.
• W1489652016 hasConcept C127413603 @default.
• W1489652016 hasConcept C203014093 @default.
• W1489652016 hasConcept C2780645631 @default.
• W1489652016 hasConcept C2781197716 @default.
• W1489652016 hasConcept C2908647359 @default.
• W1489652016 hasConcept C55493867 @default.
• W1489652016 hasConcept C58471807 @default.
• W1489652016 hasConcept C71924100 @default.
• W1489652016 hasConcept C76318530 @default.
• W1489652016 hasConcept C77350462 @default.
• W1489652016 hasConcept C78519656 @default.
• W1489652016 hasConcept C86803240 @default.
• W1489652016 hasConcept C90924648 @default.
• W1489652016 hasConcept C99454951 @default.
• W1489652016 hasConceptScore W1489652016C126322002 @default.
• W1489652016 hasConceptScore W1489652016C127413603 @default.
• W1489652016 hasConceptScore W1489652016C203014093 @default.
• W1489652016 hasConceptScore W1489652016C2780645631 @default.
• W1489652016 hasConceptScore W1489652016C2781197716 @default.
• W1489652016 hasConceptScore W1489652016C2908647359 @default.
• W1489652016 hasConceptScore W1489652016C55493867 @default.
• W1489652016 hasConceptScore W1489652016C58471807 @default.
• W1489652016 hasConceptScore W1489652016C71924100 @default.
• W1489652016 hasConceptScore W1489652016C76318530 @default.
• W1489652016 hasConceptScore W1489652016C77350462 @default.
• W1489652016 hasConceptScore W1489652016C78519656 @default.
• W1489652016 hasConceptScore W1489652016C86803240 @default.
• W1489652016 hasConceptScore W1489652016C90924648 @default.
• W1489652016 hasConceptScore W1489652016C99454951 @default.
• W1489652016 hasLocation W14896520161 @default.
• W1489652016 hasLocation W14896520162 @default.
• W1489652016 hasOpenAccess W1489652016 @default.
• W1489652016 hasPrimaryLocation W14896520161 @default.
• W1489652016 hasRelatedWork W1921717516 @default.
• W1489652016 hasRelatedWork W2085454302 @default.
• W1489652016 hasRelatedWork W2101325366 @default.
• W1489652016 hasRelatedWork W2122443163 @default.
• W1489652016 hasRelatedWork W2154039449 @default.
• W1489652016 hasRelatedWork W2307570313 @default.
• W1489652016 hasRelatedWork W2498441064 @default.

• next