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- W1489659320 abstract "The blood brain barrier (BBB) proves a major obstacle for drug delivery to the CNS and with only 1% of drugs able to penetrate the BBB, effective treatment for disorders such as Parkinson’s Disease (PD) is needed. Current therapy available for the treatment of PD gives rise to numerous side-effects and lack prolonged efficacy. A nano-enabled polymericdevice implanted into the subarachnoid cavity of the brain may circumvent these challenges as drug is targeted to the affected areas of the brain andtherefore a lower effective dose is required. The major benefit of an implantable device will be sustained release of drug which is imperative to prevent the ‘end-of-dose wearing-off’ phenomenon.The device will prove superior in that it serves to overcome the major barriers of current drug delivery systems available for the treatment of PD." @default.
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- W1489659320 date "2008-03-01" @default.
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- W1489659320 title "Young Scientist Award 2007" @default.
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