FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W148966384> ?p ?o ?g. }

• W148966384 endingPage "506" @default.
• W148966384 startingPage "491" @default.
• W148966384 abstract "The subtotal (5/6) nephrectomy performed in 23 adult female rats induced severe hypertrophy of residual parenchyma with interstitial fibrosis, tubular dilatation, and focal and segmental glomerulosclerosis (FSG). This ablation nephropathy (AbN) caused proteinuria, progressive renal failure, and hypertension. The extent of FSG was assessed by semiquantitative scoring. The ultrastructure revealed widespread foot process fusion, many dense cytoplasmic inclusions in podocytes, and degenerative changes or disruption of mesangium with glomerular microcysts. Numerous granular deposits of rat Ig were seen in the glomeruli but a short praeterminal i.v. load by heat-aggregated human Ig did not alter the morphology of AbN and produced discrete and inconstant glomerular deposits. Similarly an i.v. injection of protamine and heparin generated protamine-heparin complexes seen in various layers of glomerular capillary wall, similar to those found previously in normal rats. AbN displayed a partial irregular depletion of polyanion sites reactive with polyethylenimine in lamina rara externa. A significant increase in both glomerular and interstitial Ia+ cells and a marked predominance of W3/25+ cells in the interstitial infiltrates were documented by immunohistochemistry in the remnant kidneys. Both AbN and FSG could be largely corrected (or prevented?) by subsequent syngeneic renal transplantation (TPL; 6 animals). On the other hand a severe AbN was found in two post-ablation residues after unsuccessful TPL with graft necrosis or sclerosis.--AbN has some analogies to various chronic human nephropathies (e.g. FSG) and may explain their progression to the terminal failure. Degenerative and finally destructive mesangial lesion seems to be of prime importance in AbN." @default.
• W148966384 created "2016-06-24" @default.
• W148966384 creator A5005323235 @default.
• W148966384 creator A5007082041 @default.
• W148966384 creator A5021728410 @default.
• W148966384 creator A5078047610 @default.
• W148966384 creator A5088659952 @default.
• W148966384 date "1990-08-01" @default.
• W148966384 modified "2023-10-02" @default.
• W148966384 title "Experimental Ablation Nephropathy" @default.
• W148966384 cites W1840837207 @default.
• W148966384 cites W1982451520 @default.
• W148966384 cites W1982890507 @default.
• W148966384 cites W1987203531 @default.
• W148966384 cites W1992286264 @default.
• W148966384 cites W1997664793 @default.
• W148966384 cites W1998953587 @default.
• W148966384 cites W2000648464 @default.
• W148966384 cites W2003970607 @default.
• W148966384 cites W2007285090 @default.
• W148966384 cites W2011057465 @default.
• W148966384 cites W2012896124 @default.
• W148966384 cites W2015211475 @default.
• W148966384 cites W2018160443 @default.
• W148966384 cites W2018186885 @default.
• W148966384 cites W2023397101 @default.
• W148966384 cites W2028638410 @default.
• W148966384 cites W2030089656 @default.
• W148966384 cites W2031281956 @default.
• W148966384 cites W2031696517 @default.
• W148966384 cites W2033700934 @default.
• W148966384 cites W2033906801 @default.
• W148966384 cites W2038261057 @default.
• W148966384 cites W2041383536 @default.
• W148966384 cites W2042180593 @default.
• W148966384 cites W2042299366 @default.
• W148966384 cites W2043675278 @default.
• W148966384 cites W2047061597 @default.
• W148966384 cites W2050594335 @default.
• W148966384 cites W2050864225 @default.
• W148966384 cites W2052865379 @default.
• W148966384 cites W2053097440 @default.
• W148966384 cites W2055296168 @default.
• W148966384 cites W2063033753 @default.
• W148966384 cites W2064297737 @default.
• W148966384 cites W2065207986 @default.
• W148966384 cites W2072954278 @default.
• W148966384 cites W2076996477 @default.
• W148966384 cites W2079544679 @default.
• W148966384 cites W2081379495 @default.
• W148966384 cites W2084523333 @default.
• W148966384 cites W2087167475 @default.
• W148966384 cites W2090654368 @default.
• W148966384 cites W2091635516 @default.
• W148966384 cites W2095147770 @default.
• W148966384 cites W2110740250 @default.
• W148966384 cites W2127684770 @default.
• W148966384 cites W2140892076 @default.
• W148966384 cites W2163171678 @default.
• W148966384 cites W2168234252 @default.
• W148966384 cites W2324000942 @default.
• W148966384 cites W2325329267 @default.
• W148966384 cites W2332438246 @default.
• W148966384 cites W2429685074 @default.
• W148966384 cites W4237828570 @default.
• W148966384 doi "https://doi.org/10.1016/s0344-0338(11)80469-3" @default.
• W148966384 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1701048" @default.
• W148966384 hasPublicationYear "1990" @default.
• W148966384 type Work @default.
• W148966384 sameAs 148966384 @default.
• W148966384 citedByCount "6" @default.
• W148966384 countsByYear W1489663842014 @default.
• W148966384 countsByYear W1489663842021 @default.
• W148966384 crossrefType "journal-article" @default.
• W148966384 hasAuthorship W148966384A5005323235 @default.
• W148966384 hasAuthorship W148966384A5007082041 @default.
• W148966384 hasAuthorship W148966384A5021728410 @default.
• W148966384 hasAuthorship W148966384A5078047610 @default.
• W148966384 hasAuthorship W148966384A5088659952 @default.
• W148966384 hasConcept C126322002 @default.
• W148966384 hasConcept C134018914 @default.
• W148966384 hasConcept C142724271 @default.
• W148966384 hasConcept C2777390665 @default.
• W148966384 hasConcept C2777557582 @default.
• W148966384 hasConcept C2778415529 @default.
• W148966384 hasConcept C2779354726 @default.
• W148966384 hasConcept C2779561371 @default.
• W148966384 hasConcept C2779937669 @default.
• W148966384 hasConcept C2780091579 @default.
• W148966384 hasConcept C2780368995 @default.
• W148966384 hasConcept C2780559512 @default.
• W148966384 hasConcept C2780835560 @default.
• W148966384 hasConcept C2781184683 @default.
• W148966384 hasConcept C555293320 @default.
• W148966384 hasConcept C71924100 @default.
• W148966384 hasConceptScore W148966384C126322002 @default.
• W148966384 hasConceptScore W148966384C134018914 @default.
• W148966384 hasConceptScore W148966384C142724271 @default.

• next