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• W1489693485 abstract "Article1 February 1956ON THE CHOICE OF TREATMENT FOR HYPERTHYROIDISME. PERRY MCCULLAGH, M.D., F.A.C.P.E. PERRY MCCULLAGH, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-44-2-292 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptDuring the last 50 years there have been repeated sweeping changes in the management of hyperthyroidism. The changes have veered from emphasis on radical surgery to conservative surgery, away from surgery altogether and toward medicine, and away from medicine toward radioactive iodine. The emphasis probably will continue to shift until the etiology of hyperthyroidism has been established and the disease can be attacked specifically at its origin or, better still, prevented.It was in 1869 that Cheadle1reported excellent results in the treatment of hyperthyroidism with iodine, but the medical world was unconvinced. For many years recognized authorities warned against...Bibliography1. Cheadle WB: Exophthalmic goiter, St. George's Hosp. Rep. 4: 175-192, 1869. Google Scholar2. ChevalleyMcGavackKenigsbergPearson JTHSS: A four-year study of the treatment of hyperthyroidism with methimazole, J. Clin. Endocrinol. and Metabolism 14: 948-960 (Aug.) 1954. CrossrefGoogle Scholar3. Davidson LA: Clinical trial of methimazole in treatment of thyrotoxicosis, Brit. M. J. 2: 1300-1303 (Dec. 12) 1953. CrossrefMedlineGoogle Scholar4. SpechtBoehme NWEJ: Death due to agranulocytosis induced by methimazole therapy, J. A. M. A. 149: 1010-1011 (July 12) 1952. CrossrefMedlineGoogle Scholar5. CrokeBerry ARJW: Agranulocytosis occurring during methimazole (Tapazole) therapy, J. A. M. A. 148: 45-47 (Jan. 5) 1952. CrossrefGoogle Scholar6. Bartels EC: Clinical experience with a new antithyroid drug: 2-carbethoxythio-1-methylglyoxaline, J. Clin. Endocrinol. and Metabolism 13: 1305-1311 (Nov.) 1953. CrossrefGoogle Scholar7. Doniach D: Treatment of thyrotoxicosis with 'Neo-mercazole' (2-carbethoxythio-1-methylglyoxaline), Lancet 1: 873-879 (May 2) 1953. CrossrefMedlineGoogle Scholar8. FraserGarrodHannoJadresic TROMGA: Antithyroid activity and toxicity of Mercazole and Neo-mercazole, J. Clin. Endocrinol. and Metabolism 14: 1230-1244 (Oct.) 1954. CrossrefGoogle Scholar9. StanburyWyngaarden JBJB: Effect of Perchlorate on the human thyroid gland, Metabolism 1: 533-539 (Nov.) 1952. MedlineGoogle Scholar10. MorgansTrotter MEWR: Treatment of thyrotoxicosis with potassium perchlorate, Lancet 1: 749-751 (Apr. 10) 1954. CrossrefGoogle Scholar11. CatzStarr BP: Metabolic, isotopic, and pathological differences between sodium-5-iodo-2-thiouracil and thiouracil plus potassium iodide, Am. J. M. Sc. 225: 178-186 (Feb.) 1953. CrossrefMedlineGoogle Scholar12. VanderlaanCaplan WPR: On the mode of action of iodothiouracil, J. Clin. Endocrinol. and Metabolism 14: 232-241 (Feb.) 1954. CrossrefGoogle Scholar13. BoeGabrielsen JZ: Antithyroid drugs plus roentgen irradiation in the treatment of hyperthyroidism, J. Clin. Endocrinol. and Metabolism 14: 939-947 (Aug.) 1954. CrossrefGoogle Scholar14. FraserWilkinson RM: Simplified method of drug treatment for thyrotoxicosis, Brit. M. J. 1: 481-484 (Feb. 28) 1953. CrossrefMedlineGoogle Scholar15. RoseShorey EJM: Late results of treatment of thyrotoxicosis with goitrogenic compounds, J. Clin. Endocrinol. 11: 597-601 (June) 1951. CrossrefGoogle Scholar16. McCullaghHumphreyMcGarveySundgren EPDCCJV: Results of propylthiouracil therapy for hyperthyroidism, J. A. M. A. 147: 106-110 (Sept. 8) 1951. CrossrefMedlineGoogle Scholar17. Aspenström G: Late results with propylthiouracil treatment of hyperthyroidism in a goiter region, Acta med. Scandinav. 147: 63-70 (Fasc. 1) 1953. CrossrefMedlineGoogle Scholar18. FreitelbergKaunitzSilverSimonWassermanYohalem SPSSNLRSB: Hyperthyroidism: treatment with radioactive iodine, Arch. Int. Med. 85: 471-478 (Mar.) 1950. CrossrefGoogle Scholar19. Tighe WJ: Temporary hypoparathyroidism following radioactive iodine treatment for thyrotoxicosis, J. Clin. Endocrinol. 12: 1220-1222 (Sept.) 1952. CrossrefMedlineGoogle Scholar20. ChapmanCarverRobinsonEvans EMGWDRD: The collection of radioactive iodine by the human fetal thyroid, J. Clin. Endocrinol. 8: 717-720 (Sept.) 1948. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Cleveland, Ohio*Presented at the Thirty-sixth Annual Session of the American College of Physicians, Philadelphia, Pennsylvania, April 26, 1955.From the Department of Endocrinology, The Cleveland Clinic Foundation, and The Frank E. Bunts Educational Institute, Cleveland, Ohio. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byRecurrent Hyperthyroidism After Radioiodine-Induced Hypothyroidism: Report of Two Cases and Literature ReviewDie Strahlentherapie gutartiger Erkrankungen innersekretorischer DrüsenDie Strahlentherapie gutartiger Erkrankungen innersekretorischer DrüsenTHE TREATMENT OF TOXIC NODULAR GOITER WITH RADIOACTIVE IODINE: 10 YEARS' EXPERIENCE WITH 436 CASES*MILTON ELLER, M.D., SOLOMON SILVER, M.D., F.A.C.P., STEPHEN B. YOHALEM, M.D., F.A.C.P., ROBERT L. SEGAL, M.D.Treatment of Toxic Nodular Goitre with Radioactive IodineChapter I: Physical Growth 1 February 1956Volume 44, Issue 2Page: 292-301KeywordsAdenomasEndocrinologyEtiologyHyperthyroidismLesionsPregnancySurgeryThyroid ePublished: 1 December 2008 Issue Published: 1 February 1956 PDF downloadLoading ..." @default.
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