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- W1489721873 abstract "Methillin resistant staphylococci (MRS) are significant pathogens, and they are cause of morbidity and mortality in a worlwide. This resistance is mediated by the production of an altered penicillin-binding protein (PBP2a), which has a low affinity for beta-lactam antibiotic, and the gene encoding is mecA. Just a few antimicrobial agentes are available for the treatment of these infections, to date the majority of all these isolates remain susceptible to vancomycin, only drug of choise in our country for treatment of infecctions cused by MRS. The present study, was carried out in order to determine the isolation frcuency of MRS in the hospital pediatrics William Soler. A total of 128 staphylococcal isolates (32 Staphylococcus aureus y 96 coagulase-negative Staphylococci) from clinical specimens were studied. Species identification of sthaphylococci was based in the Rapi Stha (Biomeriux). The MIC values, the oxacillin agar screen and the resistance patterns of MRS against other antibiotic was determined using the recommended by the guide NCCLS. The mecA gene detection was carried out for a polymerase chain reation. The 15% of Staphylococcus aureus and 43 % coagulase-negative Staphylococci were intrinsic methicillin resistant MIC>2 µg/mL, whit the presence of the mecA gene. The MRS have a cross-resistance to other antibiotic families in special to macrolides; vancomycin resistance was not found. We recommended isolate patients with methillin resistant staphylococci infections in this hospital to prevent the spread of these organisms." @default.
- W1489721873 created "2016-06-24" @default.
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- W1489721873 date "2005-01-01" @default.
- W1489721873 modified "2023-09-27" @default.
- W1489721873 title "Frecuencia de Aislamientos de Staphylococcus spp Meticilina Resistente en el Hospital Pediátrico William Soler." @default.
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