Matches in SemOpenAlex for { <https://semopenalex.org/work/W1489738013> ?p ?o ?g. }
- W1489738013 abstract "A protein is at once the translation product of a gene, a polymer of amino acids folded in three-dimensional space, a molecular machine imparting a function, and a small – but often critical – component of the cell's physiology. Each of these facets of a protein is inherently linked to the others; yet, each is impacted by evolutionary processes differently. The evolution of the protein repertoire involves a broad variety of phenomena, many of which are understood in considerable detail. The aim of this chapter is to provide a panoramic survey of the subject, and to relate the molecular mechanisms of evolution to their effects on proteins, the genes that encode them, and the physiological networks that they populate.Keywords:Allosteric regulation;Convergent evolution;Cooperativity;Directed evolution;Divergent evolution;Gene cluster;Gene duplication;Homolog;Homologous recombination;Horizontal gene transfer;Metabolic network;Metabolic pathway;Metabolome;Multiprotein complex;Neofunctionalization;Nonsynonymous substitution;Operon;Ortholog;Paralog;Phylogenomics;Phylogeny;Point mutation;Protein domain;Protein primary structure;Protein quaternary structure;Protein repertoire;Protein secondary structure;Protein tertiary structure;Protein–protein interaction network;Proteome;Pseudogene;Regulatory network;Subfunctionalization;Synonymous substitution;Trans-splicing;Transcriptome" @default.
- W1489738013 created "2016-06-24" @default.
- W1489738013 creator A5012172477 @default.
- W1489738013 creator A5022560741 @default.
- W1489738013 creator A5059358345 @default.
- W1489738013 creator A5064067122 @default.
- W1489738013 date "2012-05-15" @default.
- W1489738013 modified "2023-10-03" @default.
- W1489738013 title "Evolution of the Protein Repertoire" @default.
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