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• W1489747249 startingPage "251" @default.
• W1489747249 abstract "BACKGROUND/OBJECTIVE: In-home automated external defibrillators (AEDs) are increasingly recommended as a means for improving survival of cardiac arrests that occur at home. The current study was conducted to explore the relationship between individuals’ risk of cardiac arrest and cost-effectiveness of in-home AED deployment. DESIGN: Markov decision model employing a societal perspective. PATIENTS: Four hypothetical cohorts of American adults 60 years of age at progressively greater risk for sudden cardiac death (SCD): 1) all adults (annual probability of SCD 0.4%); 2) adults with multiple SCD risk factors (probability 2%); 3) adults with previous myocardial infarction (probability 4%); and 4) adults with ischemic cardiomyopathy unable to receive an implantable defibrillator (probability 6%). INTERVENTION: Strategy 1: individuals suffering an in-home cardiac arrest were treated with emergency medical services equipped with AEDs (EMS-D). Strategy 2: individuals suffering an in-home cardiac arrest received initial treatment with an in-home AED, followed by EMS. RESULTS: Assuming cardiac arrest survival rates of 15% with EMS-D and 30% with AEDs, the cost per quality-adjusted life-year gained (QALY) of providing in-home AEDs to all adults 60 years of age is $216,000. Costs of providing in-home AEDs to adults with multiple risk factors (2% probability of SCD), previous myocardial infarction (4% probability), and ischemic cardiomyopathy (6% probability) are $132,000, $104,000, and $88,000, respectively. CONCLUSIONS: The cost-effectiveness of in-home AEDs is intimately linked to individuals’ risk of SCD. However, providing in-home AEDs to all adults over age 60 appears relatively expensive." @default.
• W1489747249 created "2016-06-24" @default.
• W1489747249 creator A5049202733 @default.
• W1489747249 creator A5071026390 @default.
• W1489747249 creator A5076377923 @default.
• W1489747249 creator A5087546386 @default.
• W1489747249 date "2005-03-01" @default.
• W1489747249 modified "2023-10-11" @default.
• W1489747249 title "Cost-effectiveness of in-home automated external defibrillators for individuals at increased risk of sudden cardiac death" @default.
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• W1489747249 doi "https://doi.org/10.1111/j.1525-1497.2005.40247.x" @default.
• W1489747249 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1490077" @default.
• W1489747249 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15836529" @default.
• W1489747249 hasPublicationYear "2005" @default.
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