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• W1489756912 abstract "Rapid detection and elimination of pathogens invasive to intestinal tissue is essential to avoid prolonged gut inflammation, or systemic sepsis. The discovery of transmembrane or intracytoplasmic pattern recognition receptors that detect the presence of conserved microbial macromolecular structures has significantly advanced the understanding of how metazoans respond to and eliminate bacteria that have entered the intestinal mucosa. In this review, we highlight recent advances in the field of host recognition of bacterial pathogens and subsequent mucosal innate immune response. Additionally, some bacteria are pathogenic because they have evolved sophisticated mechanisms to evade the host mucosal innate immune response. We discuss advances in identifying the mechanisms by which pathogens evade detection by dampening the immune response." @default.
• W1489756912 created "2016-06-24" @default.
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• W1489756912 date "2011-02-24" @default.
• W1489756912 modified "2023-10-07" @default.
• W1489756912 title "Recognition of bacterial pathogens and mucosal immunity" @default.
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• W1489756912 doi "https://doi.org/10.1111/j.1462-5822.2011.01579.x" @default.
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