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- W1489762227 abstract "The enantiomers of omeprazole and some of its analogues have been separated on a chiral stationary phase comprising trisphenylcarbamoylcellulose coated on 3-aminopropyl silica. The nature of the supporting silica has a crucial effect on the separations obtained. The racemisation half-life of omeprazole was estimated to be 1.3 · 102 h at 37°C. In vitro tests on isolated gastric glands from rabbits showed that both enantiomers of omeprazole had an inhibitory effect on acid formation." @default.
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- W1489762227 date "1990-01-01" @default.
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- W1489762227 title "Resolution of the enantiomers of omeprazole and some of its analogues by liquid chromatography on a trisphenylcarbamoylcellulose-based stationary phase" @default.
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- W1489762227 doi "https://doi.org/10.1016/s0378-4347(00)83781-0" @default.
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