Matches in SemOpenAlex for { <https://semopenalex.org/work/W1489779945> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W1489779945 endingPage "10" @default.
- W1489779945 startingPage "4" @default.
- W1489779945 abstract "Plasma total and unbound concentrations of thiopentone were investigated during exponentially decreasing infusions in seven patients undergoing cardiopulmonary bypass. Total plasma thiopentone concentrations reached a plateau (10.2, SD 2.1 μg|ml) soon after the initial bolus dose and commencement of the infusion. Concentrations were maintained until the onset of cardiopulmonary bypass, whereupon total plasma thiopentone concentration fell abruptly to 50.0 (SD 5.8) percent of the prebypass level. The unbound fraction of thiopentone increased from 16.6 (SD 1.9) percent before bypass to a maximum to 29.3 (SD 5.6) percent during bypass (p < 0.01), decreased to 22.9 (SD 3.3) percent at the end of bypass (p < 0.01), hut was still elevated 5–7 hours later (20.5, SD 2.5 percent). The result of the changes in binding was a smaller decline in unbound thiopentone concentration at the onset of bypass to 76.4 (SD 15.7) percent of the prebypass level. Also, unbound levels returned to the prebypass level by the end of bypass, whereas total levels remained low." @default.
- W1489779945 created "2016-06-24" @default.
- W1489779945 creator A5033015747 @default.
- W1489779945 creator A5038668375 @default.
- W1489779945 creator A5040241915 @default.
- W1489779945 creator A5070601551 @default.
- W1489779945 creator A5082690051 @default.
- W1489779945 date "1986-01-01" @default.
- W1489779945 modified "2023-10-18" @default.
- W1489779945 title "Thiopentone levels during cardiopulmonary bypass." @default.
- W1489779945 cites W1976541085 @default.
- W1489779945 cites W1977515785 @default.
- W1489779945 cites W1979306225 @default.
- W1489779945 cites W1984229786 @default.
- W1489779945 cites W1986565384 @default.
- W1489779945 cites W1988200797 @default.
- W1489779945 cites W1997905351 @default.
- W1489779945 cites W2000651658 @default.
- W1489779945 cites W2008994426 @default.
- W1489779945 cites W2015671880 @default.
- W1489779945 cites W2019965522 @default.
- W1489779945 cites W2034541943 @default.
- W1489779945 cites W2042466770 @default.
- W1489779945 cites W2050347915 @default.
- W1489779945 cites W2055387298 @default.
- W1489779945 cites W2058227587 @default.
- W1489779945 cites W2059962267 @default.
- W1489779945 cites W2074858130 @default.
- W1489779945 cites W2080707639 @default.
- W1489779945 cites W2081602222 @default.
- W1489779945 cites W2085345100 @default.
- W1489779945 cites W2112786485 @default.
- W1489779945 cites W2115912511 @default.
- W1489779945 cites W2141042980 @default.
- W1489779945 cites W2403393633 @default.
- W1489779945 cites W2502670554 @default.
- W1489779945 cites W74649421 @default.
- W1489779945 doi "https://doi.org/10.1111/j.1365-2044.1986.tb12695.x" @default.
- W1489779945 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3946775" @default.
- W1489779945 hasPublicationYear "1986" @default.
- W1489779945 type Work @default.
- W1489779945 sameAs 1489779945 @default.
- W1489779945 citedByCount "22" @default.
- W1489779945 crossrefType "journal-article" @default.
- W1489779945 hasAuthorship W1489779945A5033015747 @default.
- W1489779945 hasAuthorship W1489779945A5038668375 @default.
- W1489779945 hasAuthorship W1489779945A5040241915 @default.
- W1489779945 hasAuthorship W1489779945A5070601551 @default.
- W1489779945 hasAuthorship W1489779945A5082690051 @default.
- W1489779945 hasConcept C126322002 @default.
- W1489779945 hasConcept C2778881276 @default.
- W1489779945 hasConcept C3017575891 @default.
- W1489779945 hasConcept C3020079912 @default.
- W1489779945 hasConcept C42219234 @default.
- W1489779945 hasConcept C43376680 @default.
- W1489779945 hasConcept C71924100 @default.
- W1489779945 hasConceptScore W1489779945C126322002 @default.
- W1489779945 hasConceptScore W1489779945C2778881276 @default.
- W1489779945 hasConceptScore W1489779945C3017575891 @default.
- W1489779945 hasConceptScore W1489779945C3020079912 @default.
- W1489779945 hasConceptScore W1489779945C42219234 @default.
- W1489779945 hasConceptScore W1489779945C43376680 @default.
- W1489779945 hasConceptScore W1489779945C71924100 @default.
- W1489779945 hasIssue "1" @default.
- W1489779945 hasLocation W14897799451 @default.
- W1489779945 hasLocation W14897799452 @default.
- W1489779945 hasOpenAccess W1489779945 @default.
- W1489779945 hasPrimaryLocation W14897799451 @default.
- W1489779945 hasRelatedWork W1489779945 @default.
- W1489779945 hasRelatedWork W2055260893 @default.
- W1489779945 hasRelatedWork W2063795836 @default.
- W1489779945 hasRelatedWork W2091491103 @default.
- W1489779945 hasRelatedWork W2125975778 @default.
- W1489779945 hasRelatedWork W2133278334 @default.
- W1489779945 hasRelatedWork W2152439221 @default.
- W1489779945 hasRelatedWork W2367927558 @default.
- W1489779945 hasRelatedWork W3031439481 @default.
- W1489779945 hasRelatedWork W1970185665 @default.
- W1489779945 hasVolume "41" @default.
- W1489779945 isParatext "false" @default.
- W1489779945 isRetracted "false" @default.
- W1489779945 magId "1489779945" @default.
- W1489779945 workType "article" @default.