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- W1489887317 abstract "Abstract Infants with PTA (Types I and II) usually have growth retardation and the physical findings of a large left-to-right shunt. Cyanosis is almost always either absent or minimal. Characteristically, a loud systolic murmur along the left sternal border is present. It is preceded by a prominent constant ejection click and ends before the second sound. A diastolic flow murmur is frequently present at the apex. Continuous or truncal valve insufficiency murmurs are rare. “Splitting” of the second sound is not uncommon. This auscultatory finding may be explained because, in some patients, the second sound is “wide” being composed of several closely approximated, or indeed, 2 discrete components. The ECG usually shows atrial enlargement, a mean QRS axis between +55 and +110 degrees, combined ventricular hypertrophy, and abnormal T waves in V 6 . Isolated right or left ventricular hypertrophy is rare. A high incidence of extracardiac anomalies is found especially in patients with a left aortic arch. The typical roentgen findings are prominent vascular markings of the shunt type, in a patient with right aortic arch (50 per cent of our cases). The plain film findings in patients with left aortic arch are similar to those with complete transposition of the great vessels except that they have a straighter upper left heart border. Selective angiocardiography either with the catheter in the root of the trunk or in the right ventricle is the best diagnostic procedure to delineate the anatomic abnormalities. Absence of the right ventricular infundibulum with a single arterial trunk arising from both ventricles are the diagnostic features. At cardiac catheterization, the systemic arterial pulse pressure is generally wide reflecting the “aortic” run-off lesion. Systemic arterial oxygen saturation approaches normal in many of these infants. Differences in oxygen saturations between the pulmonary arteries and the “ascending aorta” are most likely due to preferential streaming." @default.
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- W1489887317 date "1969-01-01" @default.
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- W1489887317 title "Persistent truncus arteriosus in infancy" @default.
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- W1489887317 doi "https://doi.org/10.1016/0002-8703(69)90125-2" @default.
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