FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1490210097> ?p ?o ?g. }

• W1490210097 endingPage "402" @default.
• W1490210097 startingPage "395" @default.
• W1490210097 abstract "Peptidic radiotracers are highly potent substances for the specific in vivo imaging of various biological targets with Single Photon Emission Computed Tomography and Positron Emission Tomography. However, some radiolabeled peptides such as bombesin analogs were shown to exhibit only a limited stability, hampering a successful target visualization. One option to positively influence the stability of radiolabeled peptides is the introduction of certain artificial molecular scaffolds. In order to comparatively assess the influence of different structure elements on the stability of radiolabeled peptides and to identify those structure elements being most useful for peptide radiotracer stabilization, several monomeric and dimeric bombesin derivatives were synthesized, exhibiting differing molecular designs and the chelator NODAGA for (68) Ga-labeling. The radiolabeled peptides were evaluated regarding their in vitro stability in human serum to determine the influence of the introduced molecular scaffolds on the peptides' serum stabilities. The results of the evaluations showed that the introduction of scaffold structures and the overall molecular design have a substantial impact on the stabilities of the resulting peptidic radiotracers. But besides some general trends found using certain scaffold structures, the obtained results point to the necessity to empirically assess their influence on stability for each susceptible peptidic radiotracer individually." @default.
• W1490210097 created "2016-06-24" @default.
• W1490210097 creator A5003772548 @default.
• W1490210097 creator A5025491065 @default.
• W1490210097 creator A5033404330 @default.
• W1490210097 creator A5044741435 @default.
• W1490210097 creator A5052647484 @default.
• W1490210097 creator A5081680068 @default.
• W1490210097 creator A5089253709 @default.
• W1490210097 date "2015-07-27" @default.
• W1490210097 modified "2023-10-14" @default.
• W1490210097 title "Improving the stability of peptidic radiotracers by the introduction of artificial scaffolds: which structure element is most useful?" @default.
• W1490210097 cites W1502206987 @default.
• W1490210097 cites W1966335626 @default.
• W1490210097 cites W1969531388 @default.
• W1490210097 cites W1970496181 @default.
• W1490210097 cites W1974596673 @default.
• W1490210097 cites W1980603852 @default.
• W1490210097 cites W1999926950 @default.
• W1490210097 cites W2004383099 @default.
• W1490210097 cites W2026564498 @default.
• W1490210097 cites W2028355418 @default.
• W1490210097 cites W2041642756 @default.
• W1490210097 cites W2048598450 @default.
• W1490210097 cites W2054703028 @default.
• W1490210097 cites W2056937063 @default.
• W1490210097 cites W2062197775 @default.
• W1490210097 cites W2081710978 @default.
• W1490210097 cites W2084249136 @default.
• W1490210097 cites W2092496716 @default.
• W1490210097 cites W2108021322 @default.
• W1490210097 cites W2109311503 @default.
• W1490210097 cites W2117662997 @default.
• W1490210097 cites W2127038260 @default.
• W1490210097 cites W2141306685 @default.
• W1490210097 cites W2145102538 @default.
• W1490210097 cites W2151554282 @default.
• W1490210097 cites W2165684446 @default.
• W1490210097 cites W2313580829 @default.
• W1490210097 cites W2331853981 @default.
• W1490210097 cites W2334264339 @default.
• W1490210097 doi "https://doi.org/10.1002/jlcr.3315" @default.
• W1490210097 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26219022" @default.
• W1490210097 hasPublicationYear "2015" @default.
• W1490210097 type Work @default.
• W1490210097 sameAs 1490210097 @default.
• W1490210097 citedByCount "4" @default.
• W1490210097 countsByYear W14902100972016 @default.
• W1490210097 countsByYear W14902100972017 @default.
• W1490210097 countsByYear W14902100972020 @default.
• W1490210097 countsByYear W14902100972021 @default.
• W1490210097 crossrefType "journal-article" @default.
• W1490210097 hasAuthorship W1490210097A5003772548 @default.
• W1490210097 hasAuthorship W1490210097A5025491065 @default.
• W1490210097 hasAuthorship W1490210097A5033404330 @default.
• W1490210097 hasAuthorship W1490210097A5044741435 @default.
• W1490210097 hasAuthorship W1490210097A5052647484 @default.
• W1490210097 hasAuthorship W1490210097A5081680068 @default.
• W1490210097 hasAuthorship W1490210097A5089253709 @default.
• W1490210097 hasConcept C118303440 @default.
• W1490210097 hasConcept C12554922 @default.
• W1490210097 hasConcept C136229726 @default.
• W1490210097 hasConcept C136339569 @default.
• W1490210097 hasConcept C150903083 @default.
• W1490210097 hasConcept C166940927 @default.
• W1490210097 hasConcept C170493617 @default.
• W1490210097 hasConcept C178790620 @default.
• W1490210097 hasConcept C185592680 @default.
• W1490210097 hasConcept C202751555 @default.
• W1490210097 hasConcept C207001950 @default.
• W1490210097 hasConcept C21951064 @default.
• W1490210097 hasConcept C2778448772 @default.
• W1490210097 hasConcept C2779281246 @default.
• W1490210097 hasConcept C521977710 @default.
• W1490210097 hasConcept C55493867 @default.
• W1490210097 hasConcept C71924100 @default.
• W1490210097 hasConcept C86803240 @default.
• W1490210097 hasConcept C89429830 @default.
• W1490210097 hasConceptScore W1490210097C118303440 @default.
• W1490210097 hasConceptScore W1490210097C12554922 @default.
• W1490210097 hasConceptScore W1490210097C136229726 @default.
• W1490210097 hasConceptScore W1490210097C136339569 @default.
• W1490210097 hasConceptScore W1490210097C150903083 @default.
• W1490210097 hasConceptScore W1490210097C166940927 @default.
• W1490210097 hasConceptScore W1490210097C170493617 @default.
• W1490210097 hasConceptScore W1490210097C178790620 @default.
• W1490210097 hasConceptScore W1490210097C185592680 @default.
• W1490210097 hasConceptScore W1490210097C202751555 @default.
• W1490210097 hasConceptScore W1490210097C207001950 @default.
• W1490210097 hasConceptScore W1490210097C21951064 @default.
• W1490210097 hasConceptScore W1490210097C2778448772 @default.
• W1490210097 hasConceptScore W1490210097C2779281246 @default.
• W1490210097 hasConceptScore W1490210097C521977710 @default.
• W1490210097 hasConceptScore W1490210097C55493867 @default.
• W1490210097 hasConceptScore W1490210097C71924100 @default.
• W1490210097 hasConceptScore W1490210097C86803240 @default.
• W1490210097 hasConceptScore W1490210097C89429830 @default.
• W1490210097 hasFunder F4320320879 @default.

• next