FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W149036843> ?p ?o ?g. }

• W149036843 endingPage "605" @default.
• W149036843 startingPage "592" @default.
• W149036843 abstract "We report here results of a 3-year pilot voluntary screening program coupled with prenatal diagnosis directed to the prospective prevention of homozygous beta-thalassemia (beta-thal) in Sardinia. The screening program took two approaches: outreach community testing and hospital testing on request after a period of sensibilization. The outreach testing was very effective as, taking into account the already known number of couples at risk with an affected proband (20), 74% of the couple at risk expected (61) on the basis of the carrier rate were identified. Less effective was the hospital testing in which half of the couples at risk expected were detected (502 with the 199 without an affected proband). After nondirective genetic counseling, approximately 85% of the couples at risk, which had a pregnancy, with no statistically significant difference between those with and those without a proband, requested prenatal testing. This figure showed a steadily increase from the beginning in 1977 to 1980. All the pregnancies (42), but two carrying homozygous fetuses, were terminated on parental request. A continuous hospital survey of thal-major admissions in the different hospitals of the counties showed a steady decline in the incidence figure at birth from 1976 (1:213) to 1978 (1:290). These results showed that even in a medium-developed, rural, Catholic population screening coupled with prenatal diagnosis can be successful in the control of a fatal, recessively inherited disorder." @default.
• W149036843 created "2016-06-24" @default.
• W149036843 creator A5004204696 @default.
• W149036843 creator A5019085056 @default.
• W149036843 creator A5023088171 @default.
• W149036843 creator A5023265601 @default.
• W149036843 creator A5024070025 @default.
• W149036843 creator A5028680053 @default.
• W149036843 creator A5056902610 @default.
• W149036843 creator A5061262571 @default.
• W149036843 creator A5069709803 @default.
• W149036843 creator A5072587846 @default.
• W149036843 creator A5073383671 @default.
• W149036843 creator A5080985171 @default.
• W149036843 creator A5089307879 @default.
• W149036843 date "1981-07-01" @default.
• W149036843 modified "2023-09-27" @default.
• W149036843 title "Prevention of homozygous beta-thalassemia by carrier screening and prenatal diagnosis in Sardinia." @default.
• W149036843 cites W1543208599 @default.
• W149036843 cites W1734523411 @default.
• W149036843 cites W1735020771 @default.
• W149036843 cites W1974130168 @default.
• W149036843 cites W1991776385 @default.
• W149036843 cites W1993840368 @default.
• W149036843 cites W1999344434 @default.
• W149036843 cites W2008105605 @default.
• W149036843 cites W2008837502 @default.
• W149036843 cites W2018905245 @default.
• W149036843 cites W2022082352 @default.
• W149036843 cites W2022817732 @default.
• W149036843 cites W2036468772 @default.
• W149036843 cites W2040036758 @default.
• W149036843 cites W2040521468 @default.
• W149036843 cites W2090914552 @default.
• W149036843 cites W2091198164 @default.
• W149036843 cites W2093654420 @default.
• W149036843 cites W2116096629 @default.
• W149036843 cites W2154581482 @default.
• W149036843 cites W2402366297 @default.
• W149036843 cites W2403085675 @default.
• W149036843 cites W2408933596 @default.
• W149036843 cites W2411964769 @default.
• W149036843 cites W2417416592 @default.
• W149036843 cites W2421413352 @default.
• W149036843 cites W2443467042 @default.
• W149036843 cites W2470146375 @default.
• W149036843 cites W2896837951 @default.
• W149036843 cites W3203781928 @default.
• W149036843 cites W47960250 @default.
• W149036843 cites W591462264 @default.
• W149036843 cites W63041568 @default.
• W149036843 cites W2056109677 @default.
• W149036843 cites W4290117200 @default.
• W149036843 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1685095" @default.
• W149036843 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7258188" @default.
• W149036843 hasPublicationYear "1981" @default.
• W149036843 type Work @default.
• W149036843 sameAs 149036843 @default.
• W149036843 citedByCount "18" @default.
• W149036843 countsByYear W1490368432014 @default.
• W149036843 countsByYear W1490368432018 @default.
• W149036843 countsByYear W1490368432019 @default.
• W149036843 crossrefType "journal-article" @default.
• W149036843 hasAuthorship W149036843A5004204696 @default.
• W149036843 hasAuthorship W149036843A5019085056 @default.
• W149036843 hasAuthorship W149036843A5023088171 @default.
• W149036843 hasAuthorship W149036843A5023265601 @default.
• W149036843 hasAuthorship W149036843A5024070025 @default.
• W149036843 hasAuthorship W149036843A5028680053 @default.
• W149036843 hasAuthorship W149036843A5056902610 @default.
• W149036843 hasAuthorship W149036843A5061262571 @default.
• W149036843 hasAuthorship W149036843A5069709803 @default.
• W149036843 hasAuthorship W149036843A5072587846 @default.
• W149036843 hasAuthorship W149036843A5073383671 @default.
• W149036843 hasAuthorship W149036843A5080985171 @default.
• W149036843 hasAuthorship W149036843A5089307879 @default.
• W149036843 hasConcept C104317684 @default.
• W149036843 hasConcept C120665830 @default.
• W149036843 hasConcept C121332964 @default.
• W149036843 hasConcept C126322002 @default.
• W149036843 hasConcept C131872663 @default.
• W149036843 hasConcept C172680121 @default.
• W149036843 hasConcept C17744445 @default.
• W149036843 hasConcept C187212893 @default.
• W149036843 hasConcept C188997412 @default.
• W149036843 hasConcept C199539241 @default.
• W149036843 hasConcept C2777799968 @default.
• W149036843 hasConcept C2777940137 @default.
• W149036843 hasConcept C2778258057 @default.
• W149036843 hasConcept C2779234561 @default.
• W149036843 hasConcept C2780673598 @default.
• W149036843 hasConcept C2781400479 @default.
• W149036843 hasConcept C2908647359 @default.
• W149036843 hasConcept C501734568 @default.
• W149036843 hasConcept C54355233 @default.
• W149036843 hasConcept C61511704 @default.
• W149036843 hasConcept C64474127 @default.
• W149036843 hasConcept C71924100 @default.

• next